Bitter orange peel extract induces endoplasmic reticulum-mediated autophagy in human hepatoma cells

Bitter orange peel extract induces endoplasmic reticulum-mediated autophagy in human hepatoma cells

This study was aimed at investigating the anti-cancer effect of bitter orange peel extract (BOPE) on Hep3B, a human hepatoma cell line. Upon treatment of Hep3B cells with 6.25–100 μg/mL of BOPE for 72 h, its antiproliferative effect was shown to increase in a concentration- and time-dependent manner...

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Bibliographic Details
Main Authors:	Kuan-Hung Lu, Huey-Yin Lee, Yung-Lin Chu, Chi-Tang Ho, Lee-Yan Sheen
Format:	Article
Language:	English
Published:	Elsevier 2019-09-01
Series:	Journal of Functional Foods
Subjects:	Hepatocellular carcinoma Bitter orange peel extract Polymethoxyflavones Autophagy Combination effect
Online Access:	http://www.sciencedirect.com/science/article/pii/S1756464619303214

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