Structural dynamics of myosin 5 during processive motion revealed by interferometric scattering microscopy

Structural dynamics of myosin 5 during processive motion revealed by interferometric scattering microscopy

Myosin 5a is a dual-headed molecular motor that transports cargo along actin filaments. By following the motion of individual heads with interferometric scattering microscopy at nm spatial and ms temporal precision we found that the detached head occupies a loosely fixed position to one side of acti...

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Bibliographic Details
Main Authors:	Joanna Andrecka, Jaime Ortega Arroyo, Yasuharu Takagi, Gabrielle de Wit, Adam Fineberg, Lachlan MacKinnon, Gavin Young, James R Sellers, Philipp Kukura
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2015-03-01
Series:	eLife
Subjects:	molecular motor myosin single particle tracking
Online Access:	https://elifesciences.org/articles/05413

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