Recent Progress in the Understanding of the Effect of Sympathetic Nerves on Hair Follicle Growth

Clinical observation and experimental studies have long suggested that the perifollicular nerves have nutritional and regulatory effects on the growth, development, and physiological cycle of hair follicles (HFs), even though the concrete mechanism remains obscure. Recently, with the progress of imm...

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Main Authors: Jiarui Zhang, Ruosi Chen, Lihong Wen, Zhexiang Fan, Yilong Guo, Zhiqi Hu, Yong Miao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.736738/full
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author Jiarui Zhang
Ruosi Chen
Lihong Wen
Zhexiang Fan
Yilong Guo
Zhiqi Hu
Yong Miao
author_facet Jiarui Zhang
Ruosi Chen
Lihong Wen
Zhexiang Fan
Yilong Guo
Zhiqi Hu
Yong Miao
author_sort Jiarui Zhang
collection DOAJ
description Clinical observation and experimental studies have long suggested that the perifollicular nerves have nutritional and regulatory effects on the growth, development, and physiological cycle of hair follicles (HFs), even though the concrete mechanism remains obscure. Recently, with the progress of immunohistochemistry and molecular biology techniques, more innovation has been made in the study of the follicular sympathetic nerves and its nerve-effect factor norepinephrine affecting hair follicle stem cells. This review highlights the progress in the regulation of the sympathetic nervous system toward the growth of HFs.
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spelling doaj.art-529c64f9e0a04d7ba1283b5109c31bf92022-12-21T22:36:20ZengFrontiers Media S.A.Frontiers in Cell and Developmental Biology2296-634X2021-08-01910.3389/fcell.2021.736738736738Recent Progress in the Understanding of the Effect of Sympathetic Nerves on Hair Follicle GrowthJiarui ZhangRuosi ChenLihong WenZhexiang FanYilong GuoZhiqi HuYong MiaoClinical observation and experimental studies have long suggested that the perifollicular nerves have nutritional and regulatory effects on the growth, development, and physiological cycle of hair follicles (HFs), even though the concrete mechanism remains obscure. Recently, with the progress of immunohistochemistry and molecular biology techniques, more innovation has been made in the study of the follicular sympathetic nerves and its nerve-effect factor norepinephrine affecting hair follicle stem cells. This review highlights the progress in the regulation of the sympathetic nervous system toward the growth of HFs.https://www.frontiersin.org/articles/10.3389/fcell.2021.736738/fullsympathetic nerveshair folliclesnorepinephrinehair follicle stem cellshair growth
spellingShingle Jiarui Zhang
Ruosi Chen
Lihong Wen
Zhexiang Fan
Yilong Guo
Zhiqi Hu
Yong Miao
Recent Progress in the Understanding of the Effect of Sympathetic Nerves on Hair Follicle Growth
Frontiers in Cell and Developmental Biology
sympathetic nerves
hair follicles
norepinephrine
hair follicle stem cells
hair growth
title Recent Progress in the Understanding of the Effect of Sympathetic Nerves on Hair Follicle Growth
title_full Recent Progress in the Understanding of the Effect of Sympathetic Nerves on Hair Follicle Growth
title_fullStr Recent Progress in the Understanding of the Effect of Sympathetic Nerves on Hair Follicle Growth
title_full_unstemmed Recent Progress in the Understanding of the Effect of Sympathetic Nerves on Hair Follicle Growth
title_short Recent Progress in the Understanding of the Effect of Sympathetic Nerves on Hair Follicle Growth
title_sort recent progress in the understanding of the effect of sympathetic nerves on hair follicle growth
topic sympathetic nerves
hair follicles
norepinephrine
hair follicle stem cells
hair growth
url https://www.frontiersin.org/articles/10.3389/fcell.2021.736738/full
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