Review of spectral domain enhanced depth imaging optical coherence tomography of tumors of the choroid
Background: Spectral domain enhanced depth imaging optical coherence tomography (EDI-OCT) can provide anatomic localization of intraocular tumors. Aims: The aim was to identify topographical and intrinsic patterns of choroidal tumors on EDI-OCT. Settings and Design: Retrospective review. Materials a...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2015-01-01
|
| Series: | Indian Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2015;volume=63;issue=2;spage=117;epage=121;aulast=Shields |
| _version_ | 1811222423048028160 |
|---|---|
| author | Carol L Shields Janet Manalac Chandana Das Jarin Saktanasate Jerry A Shields |
| author_facet | Carol L Shields Janet Manalac Chandana Das Jarin Saktanasate Jerry A Shields |
| author_sort | Carol L Shields |
| collection | DOAJ |
| description | Background: Spectral domain enhanced depth imaging optical coherence tomography (EDI-OCT) can provide anatomic localization of intraocular tumors. Aims: The aim was to identify topographical and intrinsic patterns of choroidal tumors on EDI-OCT. Settings and Design: Retrospective review. Materials and Methods: Analysis of published reports and personal observations using office based EDI-OCT. Results: Using EDI-OCT, choroidal nevus displayed a smooth, dome-shaped topography with overlying retinal pigment epithelium alterations, drusen, and occasional subretinal cleft demonstrating photoreceptor loss. Small choroidal melanoma showed smooth, moderately dome-shaped topography, commonly with overlying shallow subretinal fluid that often depicted "shaggy" photoreceptors. Choroidal metastasis showed a minimally "lumpy, bumpy" surface topography and with overlying subretinal fluid and shaggy photoreceptors. Choroidal hemangioma showed a smooth, dome-shaped topography, with expansion of the affected small, medium, and large choroidal vessels. Choroidal lymphoma showed varying topography with increasing tumor thickness as "flat, rippled, or undulating (seasick)" surface. Choroidal osteoma displayed a smooth undulating surface with visible intralesional horizontal lines suggestive of bone lamellae and occasional horizontal and vertical tubules with intralesional "spongy" flecks. Choroidal melanocytosis appeared as uniformly thickened choroid with increased stromal density surrounding the normal choroidal vascular structures. Conclusions: Enhanced depth imaging-OCT can depict characteristic patterns that are suggestive of various choroidal tumors. |
| first_indexed | 2024-04-12T08:16:30Z |
| format | Article |
| id | doaj.art-529d983785cf4e1794121156cdee5091 |
| institution | Directory Open Access Journal |
| issn | 0301-4738 1998-3689 |
| language | English |
| last_indexed | 2024-04-12T08:16:30Z |
| publishDate | 2015-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-529d983785cf4e1794121156cdee50912022-12-22T03:40:47ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892015-01-0163211712110.4103/0301-4738.154377Review of spectral domain enhanced depth imaging optical coherence tomography of tumors of the choroidCarol L ShieldsJanet ManalacChandana DasJarin SaktanasateJerry A ShieldsBackground: Spectral domain enhanced depth imaging optical coherence tomography (EDI-OCT) can provide anatomic localization of intraocular tumors. Aims: The aim was to identify topographical and intrinsic patterns of choroidal tumors on EDI-OCT. Settings and Design: Retrospective review. Materials and Methods: Analysis of published reports and personal observations using office based EDI-OCT. Results: Using EDI-OCT, choroidal nevus displayed a smooth, dome-shaped topography with overlying retinal pigment epithelium alterations, drusen, and occasional subretinal cleft demonstrating photoreceptor loss. Small choroidal melanoma showed smooth, moderately dome-shaped topography, commonly with overlying shallow subretinal fluid that often depicted "shaggy" photoreceptors. Choroidal metastasis showed a minimally "lumpy, bumpy" surface topography and with overlying subretinal fluid and shaggy photoreceptors. Choroidal hemangioma showed a smooth, dome-shaped topography, with expansion of the affected small, medium, and large choroidal vessels. Choroidal lymphoma showed varying topography with increasing tumor thickness as "flat, rippled, or undulating (seasick)" surface. Choroidal osteoma displayed a smooth undulating surface with visible intralesional horizontal lines suggestive of bone lamellae and occasional horizontal and vertical tubules with intralesional "spongy" flecks. Choroidal melanocytosis appeared as uniformly thickened choroid with increased stromal density surrounding the normal choroidal vascular structures. Conclusions: Enhanced depth imaging-OCT can depict characteristic patterns that are suggestive of various choroidal tumors.http://www.ijo.in/article.asp?issn=0301-4738;year=2015;volume=63;issue=2;spage=117;epage=121;aulast=ShieldsCiliary bodychoroideyeirismelanomametastasisprognosistumoruveaChemotherapyintravitreal chemotherapyintra-arterial chemotherapyintravenous chemotherapyperiocular chemotherapyretinoblastomaSubtenon′s chemotherapytreatmentAutoflouroscenceenhanced depth imagingeyegene expression profilingmalignancymetastasismonosomy 3nevusoptical coherence tomographytumoruveal melanomaChoroidenhanced depth imaging optical coherence tomographyhemangiomalymphomamelanocytosismelanomametastasisnevusosteomatumor |
| spellingShingle | Carol L Shields Janet Manalac Chandana Das Jarin Saktanasate Jerry A Shields Review of spectral domain enhanced depth imaging optical coherence tomography of tumors of the choroid Indian Journal of Ophthalmology Ciliary body choroid eye iris melanoma metastasis prognosis tumor uvea Chemotherapy intravitreal chemotherapy intra-arterial chemotherapy intravenous chemotherapy periocular chemotherapy retinoblastoma Subtenon′s chemotherapy treatment Autoflouroscence enhanced depth imaging eye gene expression profiling malignancy metastasis monosomy 3 nevus optical coherence tomography tumor uveal melanoma Choroid enhanced depth imaging optical coherence tomography hemangioma lymphoma melanocytosis melanoma metastasis nevus osteoma tumor |
| title | Review of spectral domain enhanced depth imaging optical coherence tomography of tumors of the choroid |
| title_full | Review of spectral domain enhanced depth imaging optical coherence tomography of tumors of the choroid |
| title_fullStr | Review of spectral domain enhanced depth imaging optical coherence tomography of tumors of the choroid |
| title_full_unstemmed | Review of spectral domain enhanced depth imaging optical coherence tomography of tumors of the choroid |
| title_short | Review of spectral domain enhanced depth imaging optical coherence tomography of tumors of the choroid |
| title_sort | review of spectral domain enhanced depth imaging optical coherence tomography of tumors of the choroid |
| topic | Ciliary body choroid eye iris melanoma metastasis prognosis tumor uvea Chemotherapy intravitreal chemotherapy intra-arterial chemotherapy intravenous chemotherapy periocular chemotherapy retinoblastoma Subtenon′s chemotherapy treatment Autoflouroscence enhanced depth imaging eye gene expression profiling malignancy metastasis monosomy 3 nevus optical coherence tomography tumor uveal melanoma Choroid enhanced depth imaging optical coherence tomography hemangioma lymphoma melanocytosis melanoma metastasis nevus osteoma tumor |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2015;volume=63;issue=2;spage=117;epage=121;aulast=Shields |
| work_keys_str_mv | AT carollshields reviewofspectraldomainenhanceddepthimagingopticalcoherencetomographyoftumorsofthechoroid AT janetmanalac reviewofspectraldomainenhanceddepthimagingopticalcoherencetomographyoftumorsofthechoroid AT chandanadas reviewofspectraldomainenhanceddepthimagingopticalcoherencetomographyoftumorsofthechoroid AT jarinsaktanasate reviewofspectraldomainenhanceddepthimagingopticalcoherencetomographyoftumorsofthechoroid AT jerryashields reviewofspectraldomainenhanceddepthimagingopticalcoherencetomographyoftumorsofthechoroid |