Guided internet-based cognitive behavioral therapy for adolescent anxiety: Predictors of treatment response

Background: Guided internet-based cognitive behavioral therapy (ICBT) has been found efficacious in reducing symptoms of anxiety in adolescents with anxiety disorders, but not all respond equally well. Objective: In this study, we explored candidate predictors of ICBT treatment response within the f...

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Main Authors: Silke Stjerneklar, Esben Hougaard, Mikael Thastum
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Internet Interventions
Online Access:http://www.sciencedirect.com/science/article/pii/S2214782918300435
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author Silke Stjerneklar
Esben Hougaard
Mikael Thastum
author_facet Silke Stjerneklar
Esben Hougaard
Mikael Thastum
author_sort Silke Stjerneklar
collection DOAJ
description Background: Guided internet-based cognitive behavioral therapy (ICBT) has been found efficacious in reducing symptoms of anxiety in adolescents with anxiety disorders, but not all respond equally well. Objective: In this study, we explored candidate predictors of ICBT treatment response within the frame of a randomized controlled trial. Methods: Sixty-five adolescents (13–17 years) with anxiety disorders according to DSM-IV received 14 weeks of therapist-guided ICBT. Outcome was evaluated as improvement (continuous change score) from pre-treatment to 12-month follow-up according to self-reported anxiety symptoms and clinician-rated diagnostic severity. Clinical predictors included baseline self- and parent-reported anxiety symptom levels, baseline clinician-rated severity of primary diagnosis, summed baseline clinician-rated severity of all anxiety diagnoses, baseline self-rated depressive symptoms, age of onset, and primary diagnosis of social phobia. Demographic predictors included age, gender and computer comfortability. Therapy process-related predictors included number of completed modules and therapist phone calls, summed duration of therapist phone calls, degree of parent support, and therapeutic alliance. Multi-level models were used to test the prediction effects over time. Results: Higher levels of self- and clinician-rated baseline anxiety and self-rated depressive symptoms, female gender, and higher levels of computer comfortability were associated with increased treatment response. None of the proposed therapy process-related predictors significantly predicted treatment response. Conclusion: The present findings indicate that ICBT may be an acceptable choice of treatment for youths, even those with relative high levels of anxiety and depressive symptoms. Keywords: Anxiety disorders, Internet-based, Cognitive behavioral therapy, Adolescents, Predictors, Treatment response
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spelling doaj.art-52a036d3b3cd4bf0b846c532bc573c802022-12-22T03:11:01ZengElsevierInternet Interventions2214-78292019-03-0115116125Guided internet-based cognitive behavioral therapy for adolescent anxiety: Predictors of treatment responseSilke Stjerneklar0Esben Hougaard1Mikael Thastum2Corresponding author at: Dep. of Psychology and Behavioral Sciences, Aarhus BSS, Aarhus University, Bartholins Allé 13, building 1343, room 393, 8000 Aarhus C, Denmark.; Department of Psychology and Behavioral Sciences, Aarhus BSS, Aarhus University, Bartholins Allé 9, 8000 Aarhus C, DenmarkDepartment of Psychology and Behavioral Sciences, Aarhus BSS, Aarhus University, Bartholins Allé 9, 8000 Aarhus C, DenmarkDepartment of Psychology and Behavioral Sciences, Aarhus BSS, Aarhus University, Bartholins Allé 9, 8000 Aarhus C, DenmarkBackground: Guided internet-based cognitive behavioral therapy (ICBT) has been found efficacious in reducing symptoms of anxiety in adolescents with anxiety disorders, but not all respond equally well. Objective: In this study, we explored candidate predictors of ICBT treatment response within the frame of a randomized controlled trial. Methods: Sixty-five adolescents (13–17 years) with anxiety disorders according to DSM-IV received 14 weeks of therapist-guided ICBT. Outcome was evaluated as improvement (continuous change score) from pre-treatment to 12-month follow-up according to self-reported anxiety symptoms and clinician-rated diagnostic severity. Clinical predictors included baseline self- and parent-reported anxiety symptom levels, baseline clinician-rated severity of primary diagnosis, summed baseline clinician-rated severity of all anxiety diagnoses, baseline self-rated depressive symptoms, age of onset, and primary diagnosis of social phobia. Demographic predictors included age, gender and computer comfortability. Therapy process-related predictors included number of completed modules and therapist phone calls, summed duration of therapist phone calls, degree of parent support, and therapeutic alliance. Multi-level models were used to test the prediction effects over time. Results: Higher levels of self- and clinician-rated baseline anxiety and self-rated depressive symptoms, female gender, and higher levels of computer comfortability were associated with increased treatment response. None of the proposed therapy process-related predictors significantly predicted treatment response. Conclusion: The present findings indicate that ICBT may be an acceptable choice of treatment for youths, even those with relative high levels of anxiety and depressive symptoms. Keywords: Anxiety disorders, Internet-based, Cognitive behavioral therapy, Adolescents, Predictors, Treatment responsehttp://www.sciencedirect.com/science/article/pii/S2214782918300435
spellingShingle Silke Stjerneklar
Esben Hougaard
Mikael Thastum
Guided internet-based cognitive behavioral therapy for adolescent anxiety: Predictors of treatment response
Internet Interventions
title Guided internet-based cognitive behavioral therapy for adolescent anxiety: Predictors of treatment response
title_full Guided internet-based cognitive behavioral therapy for adolescent anxiety: Predictors of treatment response
title_fullStr Guided internet-based cognitive behavioral therapy for adolescent anxiety: Predictors of treatment response
title_full_unstemmed Guided internet-based cognitive behavioral therapy for adolescent anxiety: Predictors of treatment response
title_short Guided internet-based cognitive behavioral therapy for adolescent anxiety: Predictors of treatment response
title_sort guided internet based cognitive behavioral therapy for adolescent anxiety predictors of treatment response
url http://www.sciencedirect.com/science/article/pii/S2214782918300435
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