Diffuse Correlation Spectroscopy: A Review of Recent Advances in Parallelisation and Depth Discrimination Techniques

Diffuse correlation spectroscopy is a non-invasive optical modality used to measure cerebral blood flow in real time, and it has important potential applications in clinical monitoring and neuroscience. As such, many research groups have recently been investigating methods to improve the signal-to-n...

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Main Authors: Edward James, Peter R. T. Munro
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Sensors
Subjects:
Online Access:https://www.mdpi.com/1424-8220/23/23/9338
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author Edward James
Peter R. T. Munro
author_facet Edward James
Peter R. T. Munro
author_sort Edward James
collection DOAJ
description Diffuse correlation spectroscopy is a non-invasive optical modality used to measure cerebral blood flow in real time, and it has important potential applications in clinical monitoring and neuroscience. As such, many research groups have recently been investigating methods to improve the signal-to-noise ratio, imaging depth, and spatial resolution of diffuse correlation spectroscopy. Such methods have included multispeckle, long wavelength, interferometric, depth discrimination, time-of-flight resolution, and acousto-optic detection strategies. In this review, we exhaustively appraise this plethora of recent advances, which can be used to assess limitations and guide innovation for future implementations of diffuse correlation spectroscopy that will harness technological improvements in the years to come.
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spelling doaj.art-52a337072d924edeaf69683a99e7708c2023-12-08T15:25:31ZengMDPI AGSensors1424-82202023-11-012323933810.3390/s23239338Diffuse Correlation Spectroscopy: A Review of Recent Advances in Parallelisation and Depth Discrimination TechniquesEdward James0Peter R. T. Munro1Department of Medical Physics and Biomedical Engineering, University College London, London WC1E 6BT, UKDepartment of Medical Physics and Biomedical Engineering, University College London, London WC1E 6BT, UKDiffuse correlation spectroscopy is a non-invasive optical modality used to measure cerebral blood flow in real time, and it has important potential applications in clinical monitoring and neuroscience. As such, many research groups have recently been investigating methods to improve the signal-to-noise ratio, imaging depth, and spatial resolution of diffuse correlation spectroscopy. Such methods have included multispeckle, long wavelength, interferometric, depth discrimination, time-of-flight resolution, and acousto-optic detection strategies. In this review, we exhaustively appraise this plethora of recent advances, which can be used to assess limitations and guide innovation for future implementations of diffuse correlation spectroscopy that will harness technological improvements in the years to come.https://www.mdpi.com/1424-8220/23/23/9338diffuse correlation spectroscopycerebral blood flowlaser speckle
spellingShingle Edward James
Peter R. T. Munro
Diffuse Correlation Spectroscopy: A Review of Recent Advances in Parallelisation and Depth Discrimination Techniques
Sensors
diffuse correlation spectroscopy
cerebral blood flow
laser speckle
title Diffuse Correlation Spectroscopy: A Review of Recent Advances in Parallelisation and Depth Discrimination Techniques
title_full Diffuse Correlation Spectroscopy: A Review of Recent Advances in Parallelisation and Depth Discrimination Techniques
title_fullStr Diffuse Correlation Spectroscopy: A Review of Recent Advances in Parallelisation and Depth Discrimination Techniques
title_full_unstemmed Diffuse Correlation Spectroscopy: A Review of Recent Advances in Parallelisation and Depth Discrimination Techniques
title_short Diffuse Correlation Spectroscopy: A Review of Recent Advances in Parallelisation and Depth Discrimination Techniques
title_sort diffuse correlation spectroscopy a review of recent advances in parallelisation and depth discrimination techniques
topic diffuse correlation spectroscopy
cerebral blood flow
laser speckle
url https://www.mdpi.com/1424-8220/23/23/9338
work_keys_str_mv AT edwardjames diffusecorrelationspectroscopyareviewofrecentadvancesinparallelisationanddepthdiscriminationtechniques
AT peterrtmunro diffusecorrelationspectroscopyareviewofrecentadvancesinparallelisationanddepthdiscriminationtechniques