Transcriptomics and Targeted Proteomics Analysis to Gain Insights Into the Immune-control Mechanisms of HIV-1 Infected Elite Controllers

Transcriptomics and Targeted Proteomics Analysis to Gain Insights Into the Immune-control Mechanisms of HIV-1 Infected Elite Controllers

A small subset of HIV-1 infected individuals, the “Elite Controllers” (EC), can control viral replication and restrain progression to immunodeficiency without antiretroviral therapy (ART). In this study, a cross-sectional transcriptomics and targeted proteomics analysis were performed in a well-defi...

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Bibliographic Details
Main Authors: Wang Zhang, Anoop T. Ambikan, Maike Sperk, Robert van Domselaar, Piotr Nowak, Kajsa Noyan, Aman Russom, Anders Sönnerborg, Ujjwal Neogi
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:EBioMedicine
Subjects:
HIV-1 Elite Controllers
Transcriptome
Proteome
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396417304735

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