Retrograde Transvenous Obliteration of Gastric Varices using Sodium Tetradecyl Sulphate: Technical Considerations and Results from a Single Institution Retrospective Study

Introduction Retrograde transvenous obliteration (RTO) with the assistance of a balloon (BRTO) or a vascular plug (PARTO) is an established method for treating gastric varices (GVs) secondary to portal hypertension. Most of the available studies on RTO have used lipiodol along with sclerosing agents...

Full description

Bibliographic Details
Main Authors: Pushpinder S. Khera, Pawan K. Garg, Sarbesh Tiwari, Narendra Bhargava, Taruna Yadav, Binit Sureka, Tushar Ghosh, Santhosh Babu, Sunil Dadhich, Surjit Singh
Format: Article
Language:English
Published: Thieme Medical Publishers, Inc. 2022-04-01
Series:Journal of Clinical Interventional Radiology ISVIR
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1728998
_version_ 1818365944267800576
author Pushpinder S. Khera
Pawan K. Garg
Sarbesh Tiwari
Narendra Bhargava
Taruna Yadav
Binit Sureka
Tushar Ghosh
Santhosh Babu
Sunil Dadhich
Surjit Singh
author_facet Pushpinder S. Khera
Pawan K. Garg
Sarbesh Tiwari
Narendra Bhargava
Taruna Yadav
Binit Sureka
Tushar Ghosh
Santhosh Babu
Sunil Dadhich
Surjit Singh
author_sort Pushpinder S. Khera
collection DOAJ
description Introduction Retrograde transvenous obliteration (RTO) with the assistance of a balloon (BRTO) or a vascular plug (PARTO) is an established method for treating gastric varices (GVs) secondary to portal hypertension. Most of the available studies on RTO have used lipiodol along with sclerosing agents like ethanolamine oleate or sodium tetradecyl sulfate (STS). We evaluated the safety and efficacy of RTO for treating GVs using STS as a sclerosant without lipiodol. Materials and Methods Sixteen patients (nine men, age range 16–74 years) were included in this retrospective study. Twelve patients presented with acute bleeding, two with chronic bleeding, one with large varices without bleeding, and one with refractory hepatic encephalopathy (HE). BRTO was attempted in 14 patients and PARTO in 2 patients. The technical and clinical success and complications of RTO were studied. Results The RTO procedure was technically successful in 14 (14/16, 87.5%) patients, with 13 (13/14, 93%) obtaining clinical success. One patient died due to the early recurrence of bleeding. Three patients had minor intraprocedural complications. Conclusion Retrograde gastric variceal obliteration using STS is safe and technically feasible with high technical and clinical success and low complication rate.
first_indexed 2024-12-13T22:28:18Z
format Article
id doaj.art-52a9a85fb8c14a13ae893a9a0b36904f
institution Directory Open Access Journal
issn 2456-4869
language English
last_indexed 2024-12-13T22:28:18Z
publishDate 2022-04-01
publisher Thieme Medical Publishers, Inc.
record_format Article
series Journal of Clinical Interventional Radiology ISVIR
spelling doaj.art-52a9a85fb8c14a13ae893a9a0b36904f2022-12-21T23:29:08ZengThieme Medical Publishers, Inc.Journal of Clinical Interventional Radiology ISVIR2456-48692022-04-01601101710.1055/s-0041-1728998Retrograde Transvenous Obliteration of Gastric Varices using Sodium Tetradecyl Sulphate: Technical Considerations and Results from a Single Institution Retrospective StudyPushpinder S. Khera0Pawan K. Garg1Sarbesh Tiwari2Narendra Bhargava3Taruna Yadav4Binit Sureka5Tushar Ghosh6Santhosh Babu7Sunil Dadhich8Surjit Singh9Department of Diagnostic and Interventional Radiology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, IndiaDepartment of Diagnostic and Interventional Radiology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, IndiaDepartment of Diagnostic and Interventional Radiology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, IndiaDepartment of Gastroenterology, Dr S N Medical College, Jodhpur, Rajasthan, IndiaDepartment of Diagnostic and Interventional Radiology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, IndiaDepartment of Diagnostic and Interventional Radiology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, IndiaDepartment of Diagnostic and Interventional Radiology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, IndiaDepartment of Diagnostic and Interventional Radiology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, IndiaDepartment of Gastroenterology, Dr S N Medical College, Jodhpur, Rajasthan, IndiaDepartment of Pharmacology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, IndiaIntroduction Retrograde transvenous obliteration (RTO) with the assistance of a balloon (BRTO) or a vascular plug (PARTO) is an established method for treating gastric varices (GVs) secondary to portal hypertension. Most of the available studies on RTO have used lipiodol along with sclerosing agents like ethanolamine oleate or sodium tetradecyl sulfate (STS). We evaluated the safety and efficacy of RTO for treating GVs using STS as a sclerosant without lipiodol. Materials and Methods Sixteen patients (nine men, age range 16–74 years) were included in this retrospective study. Twelve patients presented with acute bleeding, two with chronic bleeding, one with large varices without bleeding, and one with refractory hepatic encephalopathy (HE). BRTO was attempted in 14 patients and PARTO in 2 patients. The technical and clinical success and complications of RTO were studied. Results The RTO procedure was technically successful in 14 (14/16, 87.5%) patients, with 13 (13/14, 93%) obtaining clinical success. One patient died due to the early recurrence of bleeding. Three patients had minor intraprocedural complications. Conclusion Retrograde gastric variceal obliteration using STS is safe and technically feasible with high technical and clinical success and low complication rate.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1728998bleeding gastric varicesretrograde transvenous obliterationballoon-occluded retrograde transvenous obliterationplug-assisted retrograde transvenous obliterationgastrorenal shunthepatic encephalopathysodium tetradecyl sulfate
spellingShingle Pushpinder S. Khera
Pawan K. Garg
Sarbesh Tiwari
Narendra Bhargava
Taruna Yadav
Binit Sureka
Tushar Ghosh
Santhosh Babu
Sunil Dadhich
Surjit Singh
Retrograde Transvenous Obliteration of Gastric Varices using Sodium Tetradecyl Sulphate: Technical Considerations and Results from a Single Institution Retrospective Study
Journal of Clinical Interventional Radiology ISVIR
bleeding gastric varices
retrograde transvenous obliteration
balloon-occluded retrograde transvenous obliteration
plug-assisted retrograde transvenous obliteration
gastrorenal shunt
hepatic encephalopathy
sodium tetradecyl sulfate
title Retrograde Transvenous Obliteration of Gastric Varices using Sodium Tetradecyl Sulphate: Technical Considerations and Results from a Single Institution Retrospective Study
title_full Retrograde Transvenous Obliteration of Gastric Varices using Sodium Tetradecyl Sulphate: Technical Considerations and Results from a Single Institution Retrospective Study
title_fullStr Retrograde Transvenous Obliteration of Gastric Varices using Sodium Tetradecyl Sulphate: Technical Considerations and Results from a Single Institution Retrospective Study
title_full_unstemmed Retrograde Transvenous Obliteration of Gastric Varices using Sodium Tetradecyl Sulphate: Technical Considerations and Results from a Single Institution Retrospective Study
title_short Retrograde Transvenous Obliteration of Gastric Varices using Sodium Tetradecyl Sulphate: Technical Considerations and Results from a Single Institution Retrospective Study
title_sort retrograde transvenous obliteration of gastric varices using sodium tetradecyl sulphate technical considerations and results from a single institution retrospective study
topic bleeding gastric varices
retrograde transvenous obliteration
balloon-occluded retrograde transvenous obliteration
plug-assisted retrograde transvenous obliteration
gastrorenal shunt
hepatic encephalopathy
sodium tetradecyl sulfate
url http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1728998
work_keys_str_mv AT pushpinderskhera retrogradetransvenousobliterationofgastricvaricesusingsodiumtetradecylsulphatetechnicalconsiderationsandresultsfromasingleinstitutionretrospectivestudy
AT pawankgarg retrogradetransvenousobliterationofgastricvaricesusingsodiumtetradecylsulphatetechnicalconsiderationsandresultsfromasingleinstitutionretrospectivestudy
AT sarbeshtiwari retrogradetransvenousobliterationofgastricvaricesusingsodiumtetradecylsulphatetechnicalconsiderationsandresultsfromasingleinstitutionretrospectivestudy
AT narendrabhargava retrogradetransvenousobliterationofgastricvaricesusingsodiumtetradecylsulphatetechnicalconsiderationsandresultsfromasingleinstitutionretrospectivestudy
AT tarunayadav retrogradetransvenousobliterationofgastricvaricesusingsodiumtetradecylsulphatetechnicalconsiderationsandresultsfromasingleinstitutionretrospectivestudy
AT binitsureka retrogradetransvenousobliterationofgastricvaricesusingsodiumtetradecylsulphatetechnicalconsiderationsandresultsfromasingleinstitutionretrospectivestudy
AT tusharghosh retrogradetransvenousobliterationofgastricvaricesusingsodiumtetradecylsulphatetechnicalconsiderationsandresultsfromasingleinstitutionretrospectivestudy
AT santhoshbabu retrogradetransvenousobliterationofgastricvaricesusingsodiumtetradecylsulphatetechnicalconsiderationsandresultsfromasingleinstitutionretrospectivestudy
AT sunildadhich retrogradetransvenousobliterationofgastricvaricesusingsodiumtetradecylsulphatetechnicalconsiderationsandresultsfromasingleinstitutionretrospectivestudy
AT surjitsingh retrogradetransvenousobliterationofgastricvaricesusingsodiumtetradecylsulphatetechnicalconsiderationsandresultsfromasingleinstitutionretrospectivestudy