Automatic Method for Optic Disc Segmentation Using Deep Learning on Retinal Fundus Images

Objectives The optic disc is part of the retinal fundus image structure, which influences the extraction of glaucoma features. This study proposes a method that automatically segments the optic disc area in retinal fundus images using deep learning based on a convolutional neural network (CNN). Meth...

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Main Authors: Anindita Septiarini, Hamdani Hamdani, Emy Setyaningsih, Eko Junirianto, Fitri Utaminingrum
Format: Article
Language:English
Published: The Korean Society of Medical Informatics 2023-04-01
Series:Healthcare Informatics Research
Subjects:
Online Access:http://e-hir.org/upload/pdf/hir-2023-29-2-145.pdf
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author Anindita Septiarini
Hamdani Hamdani
Emy Setyaningsih
Eko Junirianto
Fitri Utaminingrum
author_facet Anindita Septiarini
Hamdani Hamdani
Emy Setyaningsih
Eko Junirianto
Fitri Utaminingrum
author_sort Anindita Septiarini
collection DOAJ
description Objectives The optic disc is part of the retinal fundus image structure, which influences the extraction of glaucoma features. This study proposes a method that automatically segments the optic disc area in retinal fundus images using deep learning based on a convolutional neural network (CNN). Methods This study used private and public datasets containing retinal fundus images. The private dataset consisted of 350 images, while the public dataset was the Retinal Fundus Glaucoma Challenge (REFUGE). The proposed method was based on a CNN with a single-shot multibox detector (MobileNetV2) to form images of the region-of-interest (ROI) using the original image resized into 640 × 640 input data. A pre-processing sequence was then implemented, including augmentation, resizing, and normalization. Furthermore, a U-Net model was applied for optic disc segmentation with 128 × 128 input data. Results The proposed method was appropriately applied to the datasets used, as shown by the values of the F1-score, dice score, and intersection over union of 0.9880, 0.9852, and 0.9763 for the private dataset, respectively, and 0.9854, 0.9838 and 0.9712 for the REFUGE dataset. Conclusions The optic disc area produced by the proposed method was similar to that identified by an ophthalmologist. Therefore, this method can be considered for implementing automatic segmentation of the optic disc area.
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spelling doaj.art-52ab8c48a62d4c798ff38a3bf6d9438b2023-05-16T06:23:33ZengThe Korean Society of Medical InformaticsHealthcare Informatics Research2093-36812093-369X2023-04-0129214515110.4258/hir.2023.29.2.1451158Automatic Method for Optic Disc Segmentation Using Deep Learning on Retinal Fundus ImagesAnindita Septiarini0Hamdani Hamdani1Emy Setyaningsih2Eko Junirianto3Fitri Utaminingrum4 Department of Informatics, Faculty of Engineering, Mulawarman University, Samarinda, Indonesia Department of Informatics, Faculty of Engineering, Mulawarman University, Samarinda, Indonesia Department of Computer, System Engineering, Institut Sains & Teknologi AKPRIND, Yogyakarta, Indonesia Departmen of Information Technology, Samarinda Polytechnic of Agriculture, Samarinda, Indonesia Computer Vision Research Group, Faculty of Computer Science, Brawijaya University, Malang, IndonesiaObjectives The optic disc is part of the retinal fundus image structure, which influences the extraction of glaucoma features. This study proposes a method that automatically segments the optic disc area in retinal fundus images using deep learning based on a convolutional neural network (CNN). Methods This study used private and public datasets containing retinal fundus images. The private dataset consisted of 350 images, while the public dataset was the Retinal Fundus Glaucoma Challenge (REFUGE). The proposed method was based on a CNN with a single-shot multibox detector (MobileNetV2) to form images of the region-of-interest (ROI) using the original image resized into 640 × 640 input data. A pre-processing sequence was then implemented, including augmentation, resizing, and normalization. Furthermore, a U-Net model was applied for optic disc segmentation with 128 × 128 input data. Results The proposed method was appropriately applied to the datasets used, as shown by the values of the F1-score, dice score, and intersection over union of 0.9880, 0.9852, and 0.9763 for the private dataset, respectively, and 0.9854, 0.9838 and 0.9712 for the REFUGE dataset. Conclusions The optic disc area produced by the proposed method was similar to that identified by an ophthalmologist. Therefore, this method can be considered for implementing automatic segmentation of the optic disc area.http://e-hir.org/upload/pdf/hir-2023-29-2-145.pdfimage processingcomputer visionfundusglaucomaoptic neuropathy
spellingShingle Anindita Septiarini
Hamdani Hamdani
Emy Setyaningsih
Eko Junirianto
Fitri Utaminingrum
Automatic Method for Optic Disc Segmentation Using Deep Learning on Retinal Fundus Images
Healthcare Informatics Research
image processing
computer vision
fundus
glaucoma
optic neuropathy
title Automatic Method for Optic Disc Segmentation Using Deep Learning on Retinal Fundus Images
title_full Automatic Method for Optic Disc Segmentation Using Deep Learning on Retinal Fundus Images
title_fullStr Automatic Method for Optic Disc Segmentation Using Deep Learning on Retinal Fundus Images
title_full_unstemmed Automatic Method for Optic Disc Segmentation Using Deep Learning on Retinal Fundus Images
title_short Automatic Method for Optic Disc Segmentation Using Deep Learning on Retinal Fundus Images
title_sort automatic method for optic disc segmentation using deep learning on retinal fundus images
topic image processing
computer vision
fundus
glaucoma
optic neuropathy
url http://e-hir.org/upload/pdf/hir-2023-29-2-145.pdf
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AT emysetyaningsih automaticmethodforopticdiscsegmentationusingdeeplearningonretinalfundusimages
AT ekojunirianto automaticmethodforopticdiscsegmentationusingdeeplearningonretinalfundusimages
AT fitriutaminingrum automaticmethodforopticdiscsegmentationusingdeeplearningonretinalfundusimages