Advances in the application of Mxene nanoparticles in wound healing
Abstract Skin is the largest organ of the human body. It plays a vital role as the body’s first barrier: stopping chemical, radiological damage and microbial invasion. The importance of skin to the human body can never be overstated. Delayed wound healing after a skin injury has become a huge challe...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-06-01
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| Series: | Journal of Biological Engineering |
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| Online Access: | https://doi.org/10.1186/s13036-023-00355-7 |
| _version_ | 1827928626420514816 |
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| author | Chengzhi Liang Jing He Yuan Cao Guoming Liu Chengdong Zhang Zhiping Qi Chuan Fu Yanling Hu |
| author_facet | Chengzhi Liang Jing He Yuan Cao Guoming Liu Chengdong Zhang Zhiping Qi Chuan Fu Yanling Hu |
| author_sort | Chengzhi Liang |
| collection | DOAJ |
| description | Abstract Skin is the largest organ of the human body. It plays a vital role as the body’s first barrier: stopping chemical, radiological damage and microbial invasion. The importance of skin to the human body can never be overstated. Delayed wound healing after a skin injury has become a huge challenge in healthcare. In some situations, this can have very serious and even life-threatening effects on people’s health. Various wound dressings have been developed to promote quicker wound healing, including hydrogels, gelatin sponges, films, and bandages, all work to prevent the invasion of microbial pathogens. Some of them are also packed with bioactive agents, such as antibiotics, nanoparticles, and growth factors, that help to improve the performance of the dressing it is added to. Recently, bioactive nanoparticles as the bioactive agent have become widely used in wound dressings. Among these, functional inorganic nanoparticles are favored due to their ability to effectively improve the tissue-repairing properties of biomaterials. MXene nanoparticles have attracted the interest of scholars due to their unique properties of electrical conductivity, hydrophilicity, antibacterial properties, and biocompatibility. The potential for its application is very promising as an effective functional component of wound dressings. In this paper, we will review MXene nanoparticles in skin injury repair, particularly its synthesis method, functional properties, biocompatibility, and application. |
| first_indexed | 2024-03-13T06:10:21Z |
| format | Article |
| id | doaj.art-52aebee7b56941b68c89b0858905b0d9 |
| institution | Directory Open Access Journal |
| issn | 1754-1611 |
| language | English |
| last_indexed | 2024-03-13T06:10:21Z |
| publishDate | 2023-06-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Biological Engineering |
| spelling | doaj.art-52aebee7b56941b68c89b0858905b0d92023-06-11T11:16:24ZengBMCJournal of Biological Engineering1754-16112023-06-0117111710.1186/s13036-023-00355-7Advances in the application of Mxene nanoparticles in wound healingChengzhi Liang0Jing He1Yuan Cao2Guoming Liu3Chengdong Zhang4Zhiping Qi5Chuan Fu6Yanling Hu7Department of Orthopedic Surgery, The Affiliated Hospital of Qingdao UniversityDepartment of Pediatric Surgery, The Affiliated Hospital of Qingdao UniversityDepartment of Orthopedic Surgery, The Affiliated Hospital of Qingdao UniversityDepartment of Orthopedic Surgery, The Affiliated Hospital of Qingdao UniversityDepartment of Orthopedic Surgery, The Affiliated Hospital of Qingdao UniversityDepartment of Orthopedic Surgery, The Second Hospital of Jilin UniversityKey Laboratory of Molecular Medicine and Biotherapy in the Ministry of Industry and Information Technology, Department of Biology, School of Life Science, Beijing Institute of TechnologyDepartment of Orthopedic Surgery, The Affiliated Hospital of Qingdao UniversityAbstract Skin is the largest organ of the human body. It plays a vital role as the body’s first barrier: stopping chemical, radiological damage and microbial invasion. The importance of skin to the human body can never be overstated. Delayed wound healing after a skin injury has become a huge challenge in healthcare. In some situations, this can have very serious and even life-threatening effects on people’s health. Various wound dressings have been developed to promote quicker wound healing, including hydrogels, gelatin sponges, films, and bandages, all work to prevent the invasion of microbial pathogens. Some of them are also packed with bioactive agents, such as antibiotics, nanoparticles, and growth factors, that help to improve the performance of the dressing it is added to. Recently, bioactive nanoparticles as the bioactive agent have become widely used in wound dressings. Among these, functional inorganic nanoparticles are favored due to their ability to effectively improve the tissue-repairing properties of biomaterials. MXene nanoparticles have attracted the interest of scholars due to their unique properties of electrical conductivity, hydrophilicity, antibacterial properties, and biocompatibility. The potential for its application is very promising as an effective functional component of wound dressings. In this paper, we will review MXene nanoparticles in skin injury repair, particularly its synthesis method, functional properties, biocompatibility, and application.https://doi.org/10.1186/s13036-023-00355-7MXeneWound dressingNanoparticlesWound healing |
| spellingShingle | Chengzhi Liang Jing He Yuan Cao Guoming Liu Chengdong Zhang Zhiping Qi Chuan Fu Yanling Hu Advances in the application of Mxene nanoparticles in wound healing Journal of Biological Engineering MXene Wound dressing Nanoparticles Wound healing |
| title | Advances in the application of Mxene nanoparticles in wound healing |
| title_full | Advances in the application of Mxene nanoparticles in wound healing |
| title_fullStr | Advances in the application of Mxene nanoparticles in wound healing |
| title_full_unstemmed | Advances in the application of Mxene nanoparticles in wound healing |
| title_short | Advances in the application of Mxene nanoparticles in wound healing |
| title_sort | advances in the application of mxene nanoparticles in wound healing |
| topic | MXene Wound dressing Nanoparticles Wound healing |
| url | https://doi.org/10.1186/s13036-023-00355-7 |
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