The Structure of Ca2+ Sensor Case16 Reveals the Mechanism of Reaction to Low Ca2+ Concentrations
Here we report the first crystal structure of a high-contrast genetically encoded circularly permuted green fluorescent protein (cpGFP)-based Ca2+ sensor, Case16, in the presence of a low Ca2+ concentration. The structure reveals the positioning of the chromophore within Case16 at the first stage of...
Main Authors: | Lydia A. Strukova, Dmitriy M. Chudakov, Olga V. Britanova, Lorenz M. Mayr, Thomas Stettler, Marco Meyerhofer, Felix Freuler, May Marsh, Wilhelm Stark, Ekaterina A. Souslova, Lukas Leder |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2010-08-01
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Series: | Sensors |
Subjects: | |
Online Access: | http://www.mdpi.com/1424-8220/10/9/8143/ |
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