Leonurus japonicus Houtt Attenuates Nonalcoholic Fatty Liver Disease in Free Fatty Acid-Induced HepG2 Cells and Mice Fed a High-Fat Diet

Leonurus japonicus Houtt Attenuates Nonalcoholic Fatty Liver Disease in Free Fatty Acid-Induced HepG2 Cells and Mice Fed a High-Fat Diet

We investigated the effects of a Leonurus japonicus ethanol extract (LJE) on nonalcoholic fatty liver disease (NAFLD). An in vitro model of hepatic steatosis was treated with 1 mM free fatty acid (FFA) in HepG2 cells. An in vivo NAFLD model was established using C57BL/6 mice fed a high-fat diet (HFD...

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Bibliographic Details
Main Authors:	Mi-Ra Lee, Kwang Il Park, Jin Yeul Ma
Format:	Article
Language:	English
Published:	MDPI AG 2017-12-01
Series:	Nutrients
Subjects:	free fatty acids HepG2 cells high-fat diet obesity Leonurus japonicus nonalcoholic fatty liver disease
Online Access:	https://www.mdpi.com/2072-6643/10/1/20

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