Genetic Analysis of SARS-CoV-2 Variants in Mexico during the First Year of the COVID-19 Pandemic
During the first year of the SARS-CoV-2 pandemic in Mexico, more than two million people were infected. In this study, we analyzed full genome sequences from 27 February 2020 to 28 February 2021 to characterize the geographical and temporal distribution of SARS-CoV-2 lineages and identify the most c...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-10-01
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| Series: | Viruses |
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| Online Access: | https://www.mdpi.com/1999-4915/13/11/2161 |
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| author | Blanca Taboada Selene Zárate Pavel Iša Celia Boukadida Joel Armando Vazquez-Perez José Esteban Muñoz-Medina José Ernesto Ramírez-González Andreu Comas-García Concepción Grajales-Muñiz Alma Rincón-Rubio Margarita Matías-Florentino Alejandro Sanchez-Flores Edgar Mendieta-Condado Jerome Verleyen Gisela Barrera-Badillo Lucía Hernández-Rivas Fidencio Mejía-Nepomuceno José Arturo Martínez-Orozco Eduardo Becerril-Vargas Susana López Irma López-Martínez Santiago Ávila-Ríos Carlos F. Arias |
| author_facet | Blanca Taboada Selene Zárate Pavel Iša Celia Boukadida Joel Armando Vazquez-Perez José Esteban Muñoz-Medina José Ernesto Ramírez-González Andreu Comas-García Concepción Grajales-Muñiz Alma Rincón-Rubio Margarita Matías-Florentino Alejandro Sanchez-Flores Edgar Mendieta-Condado Jerome Verleyen Gisela Barrera-Badillo Lucía Hernández-Rivas Fidencio Mejía-Nepomuceno José Arturo Martínez-Orozco Eduardo Becerril-Vargas Susana López Irma López-Martínez Santiago Ávila-Ríos Carlos F. Arias |
| author_sort | Blanca Taboada |
| collection | DOAJ |
| description | During the first year of the SARS-CoV-2 pandemic in Mexico, more than two million people were infected. In this study, we analyzed full genome sequences from 27 February 2020 to 28 February 2021 to characterize the geographical and temporal distribution of SARS-CoV-2 lineages and identify the most common circulating lineages during this period. We defined six different geographical regions with particular dynamics of lineage circulation. The Northeast and Northwest regions were the ones that exhibited the highest lineage diversity, while the Central south and South/Southeast regions presented less diversity with predominance of a certain lineage. Additionally, by late February 2021, lineage B.1.1.519 represented more than 89% of all circulating lineages in the country. |
| first_indexed | 2024-03-10T04:59:04Z |
| format | Article |
| id | doaj.art-52b1151d314c46e29e62f54e562f0fca |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-03-10T04:59:04Z |
| publishDate | 2021-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-52b1151d314c46e29e62f54e562f0fca2023-11-23T01:55:52ZengMDPI AGViruses1999-49152021-10-011311216110.3390/v13112161Genetic Analysis of SARS-CoV-2 Variants in Mexico during the First Year of the COVID-19 PandemicBlanca Taboada0Selene Zárate1Pavel Iša2Celia Boukadida3Joel Armando Vazquez-Perez4José Esteban Muñoz-Medina5José Ernesto Ramírez-González6Andreu Comas-García7Concepción Grajales-Muñiz8Alma Rincón-Rubio9Margarita Matías-Florentino10Alejandro Sanchez-Flores11Edgar Mendieta-Condado12Jerome Verleyen13Gisela Barrera-Badillo14Lucía Hernández-Rivas15Fidencio Mejía-Nepomuceno16José Arturo Martínez-Orozco17Eduardo Becerril-Vargas18Susana López19Irma López-Martínez20Santiago Ávila-Ríos21Carlos F. Arias22Departamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca 62210, MexicoPosgrado en Ciencias Genómicas, Universidad Autónoma de la Ciudad de México, Mexico City 03100, MexicoDepartamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca 62210, MexicoCentro de Investigación en Enfermedades Infecciosas, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, MexicoInstituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, MexicoDivisión de Laboratorios de Vigilancia e Investigación Epidemiológica, Instituto Mexicano del Seguro Social, Mexico City 07760, MexicoInstituto de Diagnóstico y Referencia Epidemiológicos, Dirección General de Epidemiología, Mexico City 01480, MexicoFacultad de Medicina y Centro de Investigación en Ciencias de la Salud y Biomedicina, Universidad Autónoma de San Luis Potosí, San Luis Potosí 78120, MexicoCoordinación de Control Técnico de Insumos, Instituto Mexicano del Seguro Social, Mexico City 07760, MexicoCentro de Investigación en Enfermedades Infecciosas, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, MexicoCentro de Investigación en Enfermedades Infecciosas, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, MexicoUnidad Universitaria de Secuenciación Masiva y Bioinformática, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca 62210, MexicoInstituto de Diagnóstico y Referencia Epidemiológicos, Dirección General de Epidemiología, Mexico City 01480, MexicoUnidad Universitaria de Secuenciación Masiva y Bioinformática, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca 62210, MexicoInstituto de Diagnóstico y Referencia Epidemiológicos, Dirección General de Epidemiología, Mexico City 01480, MexicoInstituto de Diagnóstico y Referencia Epidemiológicos, Dirección General de Epidemiología, Mexico City 01480, MexicoInstituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, MexicoInstituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, MexicoInstituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, MexicoDepartamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca 62210, MexicoInstituto de Diagnóstico y Referencia Epidemiológicos, Dirección General de Epidemiología, Mexico City 01480, MexicoCentro de Investigación en Enfermedades Infecciosas, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, MexicoDepartamento de Genética del Desarrollo y Fisiología Molecular, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Cuernavaca 62210, MexicoDuring the first year of the SARS-CoV-2 pandemic in Mexico, more than two million people were infected. In this study, we analyzed full genome sequences from 27 February 2020 to 28 February 2021 to characterize the geographical and temporal distribution of SARS-CoV-2 lineages and identify the most common circulating lineages during this period. We defined six different geographical regions with particular dynamics of lineage circulation. The Northeast and Northwest regions were the ones that exhibited the highest lineage diversity, while the Central south and South/Southeast regions presented less diversity with predominance of a certain lineage. Additionally, by late February 2021, lineage B.1.1.519 represented more than 89% of all circulating lineages in the country.https://www.mdpi.com/1999-4915/13/11/2161viral diversitySARS-CoV-2genomic surveillance |
| spellingShingle | Blanca Taboada Selene Zárate Pavel Iša Celia Boukadida Joel Armando Vazquez-Perez José Esteban Muñoz-Medina José Ernesto Ramírez-González Andreu Comas-García Concepción Grajales-Muñiz Alma Rincón-Rubio Margarita Matías-Florentino Alejandro Sanchez-Flores Edgar Mendieta-Condado Jerome Verleyen Gisela Barrera-Badillo Lucía Hernández-Rivas Fidencio Mejía-Nepomuceno José Arturo Martínez-Orozco Eduardo Becerril-Vargas Susana López Irma López-Martínez Santiago Ávila-Ríos Carlos F. Arias Genetic Analysis of SARS-CoV-2 Variants in Mexico during the First Year of the COVID-19 Pandemic Viruses viral diversity SARS-CoV-2 genomic surveillance |
| title | Genetic Analysis of SARS-CoV-2 Variants in Mexico during the First Year of the COVID-19 Pandemic |
| title_full | Genetic Analysis of SARS-CoV-2 Variants in Mexico during the First Year of the COVID-19 Pandemic |
| title_fullStr | Genetic Analysis of SARS-CoV-2 Variants in Mexico during the First Year of the COVID-19 Pandemic |
| title_full_unstemmed | Genetic Analysis of SARS-CoV-2 Variants in Mexico during the First Year of the COVID-19 Pandemic |
| title_short | Genetic Analysis of SARS-CoV-2 Variants in Mexico during the First Year of the COVID-19 Pandemic |
| title_sort | genetic analysis of sars cov 2 variants in mexico during the first year of the covid 19 pandemic |
| topic | viral diversity SARS-CoV-2 genomic surveillance |
| url | https://www.mdpi.com/1999-4915/13/11/2161 |
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