Near Fatal Anaphylactoid Reaction Due to Bupivacaine Spinal Anaesthesia

Cardiorespiratory collapse in perioperative scenario-a dreaded occurrence, can have multiple aetiologies. Among them hypersensitivity reactions although rare, contribute significantly to patient mortality. The incidence of hypersensitivity reactions during anaesthesia have been reported to a range f...

Full description

Bibliographic Details
Main Authors: Shruti Singh, Prashant Kumar Singh
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2018-03-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/11330/29288_CE(RA1)_F(T)PF1-(VJ_PY)_PFA(NC_MJ_AP)_PB(MJ_AP)_PN(AP).pdf
_version_ 1818201420553256960
author Shruti Singh
Prashant Kumar Singh
author_facet Shruti Singh
Prashant Kumar Singh
author_sort Shruti Singh
collection DOAJ
description Cardiorespiratory collapse in perioperative scenario-a dreaded occurrence, can have multiple aetiologies. Among them hypersensitivity reactions although rare, contribute significantly to patient mortality. The incidence of hypersensitivity reactions during anaesthesia have been reported to a range from 1 in 4000 to 1 in 25,000. Latex gloves and skeletal muscle relaxants are quite renowned in causing allergic reactions during perioperative period. The needle points less towards local anaesthetics, due to the rarity of such reports in literature. Also, the use of amide linked local anaesthetics for spinal anaesthesia reduces the chances of any such allergies occurring. Here, we report a case of severe anaphylactoid reaction occurring due to Bupivacaine given as a spinal anaesthetic. The extreme rarity of such reports implicating Bupivacaine as the causative agent for perioperative hypersensitivity puts this case in sharp focus. Preventing any such future episodes that are detrimental to a patient’s well-being require awareness and skill on the part of the whole team. Exploring all questionable causative agents; however, less likely or farfetched therefore becomes important.
first_indexed 2024-12-12T02:53:16Z
format Article
id doaj.art-52b24621758940c9b564c80a500c7d63
institution Directory Open Access Journal
issn 2249-782X
0973-709X
language English
last_indexed 2024-12-12T02:53:16Z
publishDate 2018-03-01
publisher JCDR Research and Publications Private Limited
record_format Article
series Journal of Clinical and Diagnostic Research
spelling doaj.art-52b24621758940c9b564c80a500c7d632022-12-22T00:40:50ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2018-03-01123UD01UD0210.7860/JCDR/2018/29288.11330Near Fatal Anaphylactoid Reaction Due to Bupivacaine Spinal AnaesthesiaShruti Singh0Prashant Kumar Singh1Senior Resident, Department of Pharmacology, All India Institutes of Medical Science, Patna, Bihar, India.Assistant Professor, Department of Surgery, All India Institutes of Medical Science, Patna, Bihar, India.Cardiorespiratory collapse in perioperative scenario-a dreaded occurrence, can have multiple aetiologies. Among them hypersensitivity reactions although rare, contribute significantly to patient mortality. The incidence of hypersensitivity reactions during anaesthesia have been reported to a range from 1 in 4000 to 1 in 25,000. Latex gloves and skeletal muscle relaxants are quite renowned in causing allergic reactions during perioperative period. The needle points less towards local anaesthetics, due to the rarity of such reports in literature. Also, the use of amide linked local anaesthetics for spinal anaesthesia reduces the chances of any such allergies occurring. Here, we report a case of severe anaphylactoid reaction occurring due to Bupivacaine given as a spinal anaesthetic. The extreme rarity of such reports implicating Bupivacaine as the causative agent for perioperative hypersensitivity puts this case in sharp focus. Preventing any such future episodes that are detrimental to a patient’s well-being require awareness and skill on the part of the whole team. Exploring all questionable causative agents; however, less likely or farfetched therefore becomes important.https://jcdr.net/articles/PDF/11330/29288_CE(RA1)_F(T)PF1-(VJ_PY)_PFA(NC_MJ_AP)_PB(MJ_AP)_PN(AP).pdfcardiac arresthypersensitivitylocal anaestheticregional anaesthesia
spellingShingle Shruti Singh
Prashant Kumar Singh
Near Fatal Anaphylactoid Reaction Due to Bupivacaine Spinal Anaesthesia
Journal of Clinical and Diagnostic Research
cardiac arrest
hypersensitivity
local anaesthetic
regional anaesthesia
title Near Fatal Anaphylactoid Reaction Due to Bupivacaine Spinal Anaesthesia
title_full Near Fatal Anaphylactoid Reaction Due to Bupivacaine Spinal Anaesthesia
title_fullStr Near Fatal Anaphylactoid Reaction Due to Bupivacaine Spinal Anaesthesia
title_full_unstemmed Near Fatal Anaphylactoid Reaction Due to Bupivacaine Spinal Anaesthesia
title_short Near Fatal Anaphylactoid Reaction Due to Bupivacaine Spinal Anaesthesia
title_sort near fatal anaphylactoid reaction due to bupivacaine spinal anaesthesia
topic cardiac arrest
hypersensitivity
local anaesthetic
regional anaesthesia
url https://jcdr.net/articles/PDF/11330/29288_CE(RA1)_F(T)PF1-(VJ_PY)_PFA(NC_MJ_AP)_PB(MJ_AP)_PN(AP).pdf
work_keys_str_mv AT shrutisingh nearfatalanaphylactoidreactionduetobupivacainespinalanaesthesia
AT prashantkumarsingh nearfatalanaphylactoidreactionduetobupivacainespinalanaesthesia