Diagnostic Use of Serum Amyloid A in Dairy Cattle

Checking the health status of the individual animal and/or herd in a farm is one of the most important factors in diary production. Because of its high economical value, the early detection of ongoing disease is of high interest in breeders and veterinary clinical practitioners. The acute phase resp...

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Main Authors: Michał Trela, Dominika Domańska, Olga Witkowska-Piłaszewicz
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Agriculture
Subjects:
Online Access:https://www.mdpi.com/2077-0472/12/4/459
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author Michał Trela
Dominika Domańska
Olga Witkowska-Piłaszewicz
author_facet Michał Trela
Dominika Domańska
Olga Witkowska-Piłaszewicz
author_sort Michał Trela
collection DOAJ
description Checking the health status of the individual animal and/or herd in a farm is one of the most important factors in diary production. Because of its high economical value, the early detection of ongoing disease is of high interest in breeders and veterinary clinical practitioners. The acute phase response (APR) is a non-specific systemic reaction for any type of tissue injury leading to disturbances in homeostasis. During this reaction, the production of acute-phase proteins (APPs) is changed. APPs may act as biomarkers of inflammation, allowing researchers to study the progression of the inflammatory response. One of the major APPs in cows is serum amyloid A (SAA). Due to its short half-life and the fast dynamic of changes in blood concentration, SAA seems to be a reliable indicator of several pathologies and treatment effectiveness. Because the blood-based and milk protein biomarkers of the herd’s health status are of great interest, this article reviews the current information about changes in SAA concentrations in the blood and milk of cattle in health and disease. It summarizes its clinical usefulness as a health status indicator in diary production.
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spelling doaj.art-52b3e2ce678844fb9ab445415da867ce2023-12-01T00:23:24ZengMDPI AGAgriculture2077-04722022-03-0112445910.3390/agriculture12040459Diagnostic Use of Serum Amyloid A in Dairy CattleMichał Trela0Dominika Domańska1Olga Witkowska-Piłaszewicz2Department of Large Animals Diseases and Clinic, Institute of Veterinary Medicine, Warsaw University of Life Sciences, Nowoursynowska 166, 02-787 Warsaw, PolandDepartment of Large Animals Diseases and Clinic, Institute of Veterinary Medicine, Warsaw University of Life Sciences, Nowoursynowska 166, 02-787 Warsaw, PolandDepartment of Large Animals Diseases and Clinic, Institute of Veterinary Medicine, Warsaw University of Life Sciences, Nowoursynowska 166, 02-787 Warsaw, PolandChecking the health status of the individual animal and/or herd in a farm is one of the most important factors in diary production. Because of its high economical value, the early detection of ongoing disease is of high interest in breeders and veterinary clinical practitioners. The acute phase response (APR) is a non-specific systemic reaction for any type of tissue injury leading to disturbances in homeostasis. During this reaction, the production of acute-phase proteins (APPs) is changed. APPs may act as biomarkers of inflammation, allowing researchers to study the progression of the inflammatory response. One of the major APPs in cows is serum amyloid A (SAA). Due to its short half-life and the fast dynamic of changes in blood concentration, SAA seems to be a reliable indicator of several pathologies and treatment effectiveness. Because the blood-based and milk protein biomarkers of the herd’s health status are of great interest, this article reviews the current information about changes in SAA concentrations in the blood and milk of cattle in health and disease. It summarizes its clinical usefulness as a health status indicator in diary production.https://www.mdpi.com/2077-0472/12/4/459cowmilk productionheard health statusAPPsSAA
spellingShingle Michał Trela
Dominika Domańska
Olga Witkowska-Piłaszewicz
Diagnostic Use of Serum Amyloid A in Dairy Cattle
Agriculture
cow
milk production
heard health status
APPs
SAA
title Diagnostic Use of Serum Amyloid A in Dairy Cattle
title_full Diagnostic Use of Serum Amyloid A in Dairy Cattle
title_fullStr Diagnostic Use of Serum Amyloid A in Dairy Cattle
title_full_unstemmed Diagnostic Use of Serum Amyloid A in Dairy Cattle
title_short Diagnostic Use of Serum Amyloid A in Dairy Cattle
title_sort diagnostic use of serum amyloid a in dairy cattle
topic cow
milk production
heard health status
APPs
SAA
url https://www.mdpi.com/2077-0472/12/4/459
work_keys_str_mv AT michałtrela diagnosticuseofserumamyloidaindairycattle
AT dominikadomanska diagnosticuseofserumamyloidaindairycattle
AT olgawitkowskapiłaszewicz diagnosticuseofserumamyloidaindairycattle