A Rare Case of Autoimmune Demyelinating Polyneuropathy and Hydrocephalus Secondary to Pembrolizumab

Pembrolizumab is a humanized monoclonal antibody that targets the programmed cell death 1 protein (PD-1) receptor and blocks the inhibitory checkpoint interaction between PD-1 and its ligands. This interaction leads to the upregulation of effector T-cells and downregulating regulatory T-cell product...

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Bibliographic Details
Main Authors: Aakriti Arora BS, Amar Shere MD, Kunal Patel MD, Nuwan Gunawardhana MD, Ericka LiFuentes MD
Format: Article
Language:English
Published: SAGE Publishing 2020-04-01
Series:Journal of Investigative Medicine High Impact Case Reports
Online Access:https://doi.org/10.1177/2324709620916358