A purified and lyophilized Pseudomonas aeruginosa derived pyocyanin induces promising apoptotic and necrotic activities against MCF-7 human breast adenocarcinoma

A purified and lyophilized Pseudomonas aeruginosa derived pyocyanin induces promising apoptotic and necrotic activities against MCF-7 human breast adenocarcinoma

Abstract Background Pyocyanin, a specific extracellular secondary metabolite pigment produced by Pseudomonas aeruginosa, exhibits redox activity and has toxic effects on mammalian cells, making it a new and potent alternative for treating cancer. Breast cancer (BC) treatment is now defied by acquire...

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Bibliographic Details
Main Authors: Ahmed A. Abdelaziz, Amal M. Abo Kamer, Khaled B. Al-Monofy, Lamiaa A. Al-Madboly
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Microbial Cell Factories
Subjects:
Bioprospection
Pyocyanin
Anticancer
Caspase-3
Human breast adenocarcinoma (MCF-7)
Online Access:https://doi.org/10.1186/s12934-022-01988-x

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