Prevalence of hepatitis-B surface antigen among blood donors and human immunodeficiency virus-infected patients in Jos, Nigeria

Information is very scarce on the prevalence of hepatitis-B virus (HBV) infection among blood donors and patients with human immunodeficiency virus (HIV) infection in Nigeria. Hepatitis-B surface antigen (HBsAg) ELISA was used to determined the prevalence of HBsAg among 175 blood donors (aged 20-40...

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Main Authors: CJ Uneke, O Ogbu, PU Inyama, GI Anyanwu, MO Njoku, JH Idoko
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2005-02-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000100002
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author CJ Uneke
O Ogbu
PU Inyama
GI Anyanwu
MO Njoku
JH Idoko
author_facet CJ Uneke
O Ogbu
PU Inyama
GI Anyanwu
MO Njoku
JH Idoko
author_sort CJ Uneke
collection DOAJ
description Information is very scarce on the prevalence of hepatitis-B virus (HBV) infection among blood donors and patients with human immunodeficiency virus (HIV) infection in Nigeria. Hepatitis-B surface antigen (HBsAg) ELISA was used to determined the prevalence of HBsAg among 175 blood donors (aged 20-40 years) and 490 HIV-infected patients (aged 17-60 years) in Jos, Nigeria. Twenty-five (14.3%) of the blood donors and 127 (25.9%) of the HIV-infected individuals were HBsAg seropositive, indicating a higher HBV infection among HIV-infected persons than among healthy blood donors. A slightly higher HBsAg seroprevalence was recorded in the males (14.6%) than females (12.9%) of the blood donors. Among the HIV-infected patients, the males had considerably higher HBsAg seroprevalence than the females (31.8 vs 22.1%) with the highest prevalence of HBsAg occurring in the 51-60 years age group (44%), followed by those of 31-40 years (28.2%). Results confirmed the high endemicity of HBV infection in Jos, Nigeria and the significantly greater prevalence of HBV infection among HIV -infected patients than among blood donors.
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spelling doaj.art-52bb541ec96d4e37b24b0393b60b58752023-08-02T09:25:54ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz0074-02761678-80602005-02-011001131610.1590/S0074-02762005000100002Prevalence of hepatitis-B surface antigen among blood donors and human immunodeficiency virus-infected patients in Jos, NigeriaCJ UnekeO OgbuPU InyamaGI AnyanwuMO NjokuJH IdokoInformation is very scarce on the prevalence of hepatitis-B virus (HBV) infection among blood donors and patients with human immunodeficiency virus (HIV) infection in Nigeria. Hepatitis-B surface antigen (HBsAg) ELISA was used to determined the prevalence of HBsAg among 175 blood donors (aged 20-40 years) and 490 HIV-infected patients (aged 17-60 years) in Jos, Nigeria. Twenty-five (14.3%) of the blood donors and 127 (25.9%) of the HIV-infected individuals were HBsAg seropositive, indicating a higher HBV infection among HIV-infected persons than among healthy blood donors. A slightly higher HBsAg seroprevalence was recorded in the males (14.6%) than females (12.9%) of the blood donors. Among the HIV-infected patients, the males had considerably higher HBsAg seroprevalence than the females (31.8 vs 22.1%) with the highest prevalence of HBsAg occurring in the 51-60 years age group (44%), followed by those of 31-40 years (28.2%). Results confirmed the high endemicity of HBV infection in Jos, Nigeria and the significantly greater prevalence of HBV infection among HIV -infected patients than among blood donors.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000100002hepatitis B virushuman immunodeficiency virusblood donorprevalence
spellingShingle CJ Uneke
O Ogbu
PU Inyama
GI Anyanwu
MO Njoku
JH Idoko
Prevalence of hepatitis-B surface antigen among blood donors and human immunodeficiency virus-infected patients in Jos, Nigeria
Memorias do Instituto Oswaldo Cruz
hepatitis B virus
human immunodeficiency virus
blood donor
prevalence
title Prevalence of hepatitis-B surface antigen among blood donors and human immunodeficiency virus-infected patients in Jos, Nigeria
title_full Prevalence of hepatitis-B surface antigen among blood donors and human immunodeficiency virus-infected patients in Jos, Nigeria
title_fullStr Prevalence of hepatitis-B surface antigen among blood donors and human immunodeficiency virus-infected patients in Jos, Nigeria
title_full_unstemmed Prevalence of hepatitis-B surface antigen among blood donors and human immunodeficiency virus-infected patients in Jos, Nigeria
title_short Prevalence of hepatitis-B surface antigen among blood donors and human immunodeficiency virus-infected patients in Jos, Nigeria
title_sort prevalence of hepatitis b surface antigen among blood donors and human immunodeficiency virus infected patients in jos nigeria
topic hepatitis B virus
human immunodeficiency virus
blood donor
prevalence
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000100002
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