High-Resolution Vessel Wall Magnetic Resonance Imaging of Small Unruptured Intracranial Aneurysms
<i>Background</i>: We decided to investigate whether aneurysm wall enhancement (AWE) on high-resolution vessel wall magnetic resonance imaging (HR VW-MRI) coexists with the conventional risk factors for aneurysm rupture. <i>Methods</i>: We performed HR VW-MRI in 46 patients w...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-01-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/10/2/225 |
| _version_ | 1797413584428335104 |
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| author | Łukasz Zwarzany Ernest Tyburski Wojciech Poncyljusz |
| author_facet | Łukasz Zwarzany Ernest Tyburski Wojciech Poncyljusz |
| author_sort | Łukasz Zwarzany |
| collection | DOAJ |
| description | <i>Background</i>: We decided to investigate whether aneurysm wall enhancement (AWE) on high-resolution vessel wall magnetic resonance imaging (HR VW-MRI) coexists with the conventional risk factors for aneurysm rupture. <i>Methods</i>: We performed HR VW-MRI in 46 patients with 64 unruptured small intracranial aneurysms. Patient demographics and clinical characteristics were recorded. The PHASES score was calculated for each aneurysm. <i>Results</i>: Of the 64 aneurysms, 15 (23.4%) showed wall enhancement on post-contrast HR VW-MRI. Aneurysms with wall enhancement had significantly larger size (<i>p</i> = 0.001), higher dome-to-neck ratio (<i>p</i> = 0.024), and a more irregular shape (<i>p</i> = 0.003) than aneurysms without wall enhancement. The proportion of aneurysms with wall enhancement was significantly higher in older patients (<i>p</i> = 0.011), and those with a history of prior aneurysmal SAH. The mean PHASES score was significantly higher in aneurysms with wall enhancement (<i>p</i> < 0.000). The multivariate logistic regression analysis revealed that aneurysm irregularity and the PHASES score are independently associated with the presence of AWE. <i>Conclusions</i>: Aneurysm wall enhancement on HR VW-MRI coexists with the conventional risk factors for aneurysm rupture. |
| first_indexed | 2024-03-09T05:20:05Z |
| format | Article |
| id | doaj.art-52bc8ac71f624f57900269dbd5a01291 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T05:20:05Z |
| publishDate | 2021-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-52bc8ac71f624f57900269dbd5a012912023-12-03T12:41:22ZengMDPI AGJournal of Clinical Medicine2077-03832021-01-0110222510.3390/jcm10020225High-Resolution Vessel Wall Magnetic Resonance Imaging of Small Unruptured Intracranial AneurysmsŁukasz Zwarzany0Ernest Tyburski1Wojciech Poncyljusz2Department of Diagnostic Imaging and Interventional Radiology, Pomeranian Medical University, Unii Lubelskiej 1, 71-252 Szczecin, PolandInstitute of Psychology, SWPS University of Social Sciences and Humanities, Kutrzeby 10, 61-719 Poznań, PolandDepartment of Diagnostic Imaging and Interventional Radiology, Pomeranian Medical University, Unii Lubelskiej 1, 71-252 Szczecin, Poland<i>Background</i>: We decided to investigate whether aneurysm wall enhancement (AWE) on high-resolution vessel wall magnetic resonance imaging (HR VW-MRI) coexists with the conventional risk factors for aneurysm rupture. <i>Methods</i>: We performed HR VW-MRI in 46 patients with 64 unruptured small intracranial aneurysms. Patient demographics and clinical characteristics were recorded. The PHASES score was calculated for each aneurysm. <i>Results</i>: Of the 64 aneurysms, 15 (23.4%) showed wall enhancement on post-contrast HR VW-MRI. Aneurysms with wall enhancement had significantly larger size (<i>p</i> = 0.001), higher dome-to-neck ratio (<i>p</i> = 0.024), and a more irregular shape (<i>p</i> = 0.003) than aneurysms without wall enhancement. The proportion of aneurysms with wall enhancement was significantly higher in older patients (<i>p</i> = 0.011), and those with a history of prior aneurysmal SAH. The mean PHASES score was significantly higher in aneurysms with wall enhancement (<i>p</i> < 0.000). The multivariate logistic regression analysis revealed that aneurysm irregularity and the PHASES score are independently associated with the presence of AWE. <i>Conclusions</i>: Aneurysm wall enhancement on HR VW-MRI coexists with the conventional risk factors for aneurysm rupture.https://www.mdpi.com/2077-0383/10/2/225unruptured intracranial aneurysmaneurysm wall enhancementvessel wall imagingMRI |
| spellingShingle | Łukasz Zwarzany Ernest Tyburski Wojciech Poncyljusz High-Resolution Vessel Wall Magnetic Resonance Imaging of Small Unruptured Intracranial Aneurysms Journal of Clinical Medicine unruptured intracranial aneurysm aneurysm wall enhancement vessel wall imaging MRI |
| title | High-Resolution Vessel Wall Magnetic Resonance Imaging of Small Unruptured Intracranial Aneurysms |
| title_full | High-Resolution Vessel Wall Magnetic Resonance Imaging of Small Unruptured Intracranial Aneurysms |
| title_fullStr | High-Resolution Vessel Wall Magnetic Resonance Imaging of Small Unruptured Intracranial Aneurysms |
| title_full_unstemmed | High-Resolution Vessel Wall Magnetic Resonance Imaging of Small Unruptured Intracranial Aneurysms |
| title_short | High-Resolution Vessel Wall Magnetic Resonance Imaging of Small Unruptured Intracranial Aneurysms |
| title_sort | high resolution vessel wall magnetic resonance imaging of small unruptured intracranial aneurysms |
| topic | unruptured intracranial aneurysm aneurysm wall enhancement vessel wall imaging MRI |
| url | https://www.mdpi.com/2077-0383/10/2/225 |
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