Click-Free Synthesis of a Multivalent Tricyclic Peptide as a Molecular Transporter

Click-Free Synthesis of a Multivalent Tricyclic Peptide as a Molecular Transporter

The cellular delivery of cell-impermeable and water-insoluble molecules remains an ongoing challenge to overcome. Previously, we reported amphipathic cyclic peptides <i>c</i>[WR]<sub>4</sub> and <i>c</i>[WR]<sub>5</sub> consisting of alternate arginine...

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Bibliographic Details
Main Authors: Sumit Kumar, Dindyal Mandal, Shaima Ahmed El-Mowafi, Saghar Mozaffari, Rakesh Kumar Tiwari, Keykavous Parang
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Pharmaceutics
Subjects:
antibacterial activity
cell-penetrating peptide
cyclic peptide
tricyclic
cellular uptake
cytotoxicity
Online Access:https://www.mdpi.com/1999-4923/12/9/842

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