Rab27a is essential for the formation of neutrophil extracellular traps (NETs) in neutrophil-like differentiated HL60 cells.

Rab27a is essential for the formation of neutrophil extracellular traps (NETs) in neutrophil-like differentiated HL60 cells.

Neutrophils play a crucial role in host defence. In response to a variety of inflammatory stimulation, they form neutrophil extracellular traps (NETs). NETs are extracellular structures composed of chromatin fibers decorated with antimicrobial proteins and developing studies indicate that NETs contr...

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Bibliographic Details
Main Authors: Tatsumi Kawakami, Jinsong He, Hiroyuki Morita, Kunio Yokoyama, Hiroaki Kaji, Chisato Tanaka, Shin-ichiro Suemori, Kaoru Tohyama, Yumi Tohyama
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3880328?pdf=render

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