Factors associated with respiratory morbidity in the first year of life
Objectives: To investigate the association between socioeconomic and nutritional factors with respiratory morbidity in the first year of life in different regions of Brazil. Methodology: A nested case-control study within a randomized field trial was conducted in three capital cities (Porto Alegre,...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-11-01
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| Series: | Jornal de Pediatria |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0021755723000773 |
| _version_ | 1797655168564592640 |
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| author | Samantha M. Lessa Daniela C. Tietzmann Sérgio L. Amantéa |
| author_facet | Samantha M. Lessa Daniela C. Tietzmann Sérgio L. Amantéa |
| author_sort | Samantha M. Lessa |
| collection | DOAJ |
| description | Objectives: To investigate the association between socioeconomic and nutritional factors with respiratory morbidity in the first year of life in different regions of Brazil. Methodology: A nested case-control study within a randomized field trial was conducted in three capital cities (Porto Alegre, Manaus, and Salvador), representing different macro-regions of the country. Cases were defined as children with a reported previous diagnosis of asthma, bronchiolitis, or pneumonia. Corresponding controls were matched by age and sex in a 2:1 ratio, selected consecutively from the original cohort, resulting in a sample of 222 children. Bivariate analyses were performed to assess the association between sociodemographic and nutritional variables with respiratory morbidity outcomes, calculating odds ratios (OR) and their respective confidence intervals (95% CI). Values of p < 0.05 were considered significant. Potential confounding factors were adjusted through multivariate analysis (logistic regression). Results: Maternal smoking and breastfeeding for less than six months showed a significant association and increased risk of respiratory disease (OR=2.12 and 2.05, respectively). Children born in the Southern region of Brazil also demonstrated a higher association and risk of respiratory morbidity. The consumption of ultra-processed foods did not show a significant association or increased risk of respiratory disease. Conclusions: Maternal smoking, breastfeeding for less than six months, and being born in the Southern region of Brazil are risk factors for the development of respiratory morbidity in the first year of life. The consumption of ultra-processed foods does not appear to pose a risk, but it was prevalent in more than 80% of the population, limiting its discriminatory power of analysis. |
| first_indexed | 2024-03-11T17:10:14Z |
| format | Article |
| id | doaj.art-52c7fff8494d4546866cd7e2b89da039 |
| institution | Directory Open Access Journal |
| issn | 0021-7557 |
| language | English |
| last_indexed | 2024-03-11T17:10:14Z |
| publishDate | 2023-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Jornal de Pediatria |
| spelling | doaj.art-52c7fff8494d4546866cd7e2b89da0392023-10-20T06:37:58ZengElsevierJornal de Pediatria0021-75572023-11-01996635640Factors associated with respiratory morbidity in the first year of lifeSamantha M. Lessa0Daniela C. Tietzmann1Sérgio L. Amantéa2Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Departamento de Pediatria, Porto Alegre, RS, Brazil; Corresponding author.Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Departamento de Nutrição, Porto Alegre, RS, BrazilUniversidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Departamento de Pediatria, Porto Alegre, RS, BrazilObjectives: To investigate the association between socioeconomic and nutritional factors with respiratory morbidity in the first year of life in different regions of Brazil. Methodology: A nested case-control study within a randomized field trial was conducted in three capital cities (Porto Alegre, Manaus, and Salvador), representing different macro-regions of the country. Cases were defined as children with a reported previous diagnosis of asthma, bronchiolitis, or pneumonia. Corresponding controls were matched by age and sex in a 2:1 ratio, selected consecutively from the original cohort, resulting in a sample of 222 children. Bivariate analyses were performed to assess the association between sociodemographic and nutritional variables with respiratory morbidity outcomes, calculating odds ratios (OR) and their respective confidence intervals (95% CI). Values of p < 0.05 were considered significant. Potential confounding factors were adjusted through multivariate analysis (logistic regression). Results: Maternal smoking and breastfeeding for less than six months showed a significant association and increased risk of respiratory disease (OR=2.12 and 2.05, respectively). Children born in the Southern region of Brazil also demonstrated a higher association and risk of respiratory morbidity. The consumption of ultra-processed foods did not show a significant association or increased risk of respiratory disease. Conclusions: Maternal smoking, breastfeeding for less than six months, and being born in the Southern region of Brazil are risk factors for the development of respiratory morbidity in the first year of life. The consumption of ultra-processed foods does not appear to pose a risk, but it was prevalent in more than 80% of the population, limiting its discriminatory power of analysis.http://www.sciencedirect.com/science/article/pii/S0021755723000773Acute respiratory infectionRisk factorsChild |
| spellingShingle | Samantha M. Lessa Daniela C. Tietzmann Sérgio L. Amantéa Factors associated with respiratory morbidity in the first year of life Jornal de Pediatria Acute respiratory infection Risk factors Child |
| title | Factors associated with respiratory morbidity in the first year of life |
| title_full | Factors associated with respiratory morbidity in the first year of life |
| title_fullStr | Factors associated with respiratory morbidity in the first year of life |
| title_full_unstemmed | Factors associated with respiratory morbidity in the first year of life |
| title_short | Factors associated with respiratory morbidity in the first year of life |
| title_sort | factors associated with respiratory morbidity in the first year of life |
| topic | Acute respiratory infection Risk factors Child |
| url | http://www.sciencedirect.com/science/article/pii/S0021755723000773 |
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