Composite lymphoma: Simultaneous development of three different lymphomas in a single patient: A clinical case

In the past decades, there has been an increase in the incidence of malignancies, including polyneoplasms. Composite synchronous lymphoma characterized by the simultaneous development of several lymphoproliferative diseases occurs very rarely. This paper describes a case of development of 3 differen...

Full description

Bibliographic Details
Main Authors: N G Chernova, Yu V Sidorova, M N Sinitsina, A B Sudarikov, A M Kovrigina, E E Zvonkov
Format: Article
Language:Russian
Published: "Consilium Medicum" Publishing house 2015-07-01
Series:Терапевтический архив
Subjects:
Online Access:https://ter-arkhiv.ru/0040-3660/article/view/31807
_version_ 1828170736277127168
author N G Chernova
Yu V Sidorova
M N Sinitsina
A B Sudarikov
A M Kovrigina
E E Zvonkov
author_facet N G Chernova
Yu V Sidorova
M N Sinitsina
A B Sudarikov
A M Kovrigina
E E Zvonkov
author_sort N G Chernova
collection DOAJ
description In the past decades, there has been an increase in the incidence of malignancies, including polyneoplasms. Composite synchronous lymphoma characterized by the simultaneous development of several lymphoproliferative diseases occurs very rarely. This paper describes a case of development of 3 different lymphomas in the same patient. Aggressive T-cell lymphoma and indolent B-cell lymphoma are diagnosed during lifetime; primary central nervous system lymphoma is verified only by examination of autopsy material. Three different lymphomas could be identified by an integrated assessment of their clinical picture and by current diagnostic techniques, such as histology, immunohistochemistry, and molecular genetics.
first_indexed 2024-04-12T03:15:19Z
format Article
id doaj.art-52d0ee5f5e8f49a59d06a34deec73e7f
institution Directory Open Access Journal
issn 0040-3660
2309-5342
language Russian
last_indexed 2024-04-12T03:15:19Z
publishDate 2015-07-01
publisher "Consilium Medicum" Publishing house
record_format Article
series Терапевтический архив
spelling doaj.art-52d0ee5f5e8f49a59d06a34deec73e7f2022-12-22T03:50:08Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422015-07-0187710110428823Composite lymphoma: Simultaneous development of three different lymphomas in a single patient: A clinical caseN G ChernovaYu V SidorovaM N SinitsinaA B SudarikovA M KovriginaE E ZvonkovIn the past decades, there has been an increase in the incidence of malignancies, including polyneoplasms. Composite synchronous lymphoma characterized by the simultaneous development of several lymphoproliferative diseases occurs very rarely. This paper describes a case of development of 3 different lymphomas in the same patient. Aggressive T-cell lymphoma and indolent B-cell lymphoma are diagnosed during lifetime; primary central nervous system lymphoma is verified only by examination of autopsy material. Three different lymphomas could be identified by an integrated assessment of their clinical picture and by current diagnostic techniques, such as histology, immunohistochemistry, and molecular genetics.https://ter-arkhiv.ru/0040-3660/article/view/31807composite lymphomaclonal rearrangementshistologicalimmunohistochemicaland molecular genetic examinations
spellingShingle N G Chernova
Yu V Sidorova
M N Sinitsina
A B Sudarikov
A M Kovrigina
E E Zvonkov
Composite lymphoma: Simultaneous development of three different lymphomas in a single patient: A clinical case
Терапевтический архив
composite lymphoma
clonal rearrangements
histological
immunohistochemical
and molecular genetic examinations
title Composite lymphoma: Simultaneous development of three different lymphomas in a single patient: A clinical case
title_full Composite lymphoma: Simultaneous development of three different lymphomas in a single patient: A clinical case
title_fullStr Composite lymphoma: Simultaneous development of three different lymphomas in a single patient: A clinical case
title_full_unstemmed Composite lymphoma: Simultaneous development of three different lymphomas in a single patient: A clinical case
title_short Composite lymphoma: Simultaneous development of three different lymphomas in a single patient: A clinical case
title_sort composite lymphoma simultaneous development of three different lymphomas in a single patient a clinical case
topic composite lymphoma
clonal rearrangements
histological
immunohistochemical
and molecular genetic examinations
url https://ter-arkhiv.ru/0040-3660/article/view/31807
work_keys_str_mv AT ngchernova compositelymphomasimultaneousdevelopmentofthreedifferentlymphomasinasinglepatientaclinicalcase
AT yuvsidorova compositelymphomasimultaneousdevelopmentofthreedifferentlymphomasinasinglepatientaclinicalcase
AT mnsinitsina compositelymphomasimultaneousdevelopmentofthreedifferentlymphomasinasinglepatientaclinicalcase
AT absudarikov compositelymphomasimultaneousdevelopmentofthreedifferentlymphomasinasinglepatientaclinicalcase
AT amkovrigina compositelymphomasimultaneousdevelopmentofthreedifferentlymphomasinasinglepatientaclinicalcase
AT eezvonkov compositelymphomasimultaneousdevelopmentofthreedifferentlymphomasinasinglepatientaclinicalcase