Peritonitis – Etiology and Treatment Options: A Systematic Review

Peritonitis is an infection with a substantial source of morbidity and death. The mortality rate is 10% to 60%. Its etiology may be infection of bacteria, viruses, or fungi. The objective of the current systematic review is to identify the causes of peritonitis and discuss available treatment opti...

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Main Authors: Sheikh Abdul Khaliq, Muhammad Idrees, Amna Zameer
Format: Article
Language:English
Published: Liaquat National Hospital and Medical College 2024-04-01
Series:Liaquat National Journal of Primary Care
Subjects:
Online Access:https://journals.lnh.edu.pk/lnjpc/pdf/7d21a528-b432-4deb-8f8f-74809e5a80af.pdf
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author Sheikh Abdul Khaliq
Muhammad Idrees
Amna Zameer
author_facet Sheikh Abdul Khaliq
Muhammad Idrees
Amna Zameer
author_sort Sheikh Abdul Khaliq
collection DOAJ
description Peritonitis is an infection with a substantial source of morbidity and death. The mortality rate is 10% to 60%. Its etiology may be infection of bacteria, viruses, or fungi. The objective of the current systematic review is to identify the causes of peritonitis and discuss available treatment options. A systematic review was conducted from the literature from January 2012 to December 2022. More than 60 articles were downloaded; after abstracting relevant information from the studies and assessing quality, data was synthesized and presented by PRISMA flow diagram. The most common cause was bacterial infection; followed by fungal and viral infections. Reported organisms were E. coli, Klebsiella spp., Streptococcus spp., M. tuberculosis, C. trachomatis, Pseudomonas spss., C. albicans, C. glabrata, C. krusei, Cryptococcus spp., and Aspergillus spp., and Feline-infectious-corona-virus. Empiric antibiotics therapy covers broad-spectrum antibacterials; antifungal and surgical interventions are treatment options. The acutely ill patient requires combined medical and surgical methods; culture sensitivity is highly advisable to reduce the chances of failure.
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spelling doaj.art-52d5e754bc7446fcb5b0d69fe1570c8d2024-01-18T07:49:38ZengLiaquat National Hospital and Medical CollegeLiaquat National Journal of Primary Care2707-35212708-91342024-04-0161667310.37184/lnjpc.2707-3521.6.2Peritonitis – Etiology and Treatment Options: A Systematic ReviewSheikh Abdul Khaliq0Muhammad Idrees1Amna Zameer2Department of Pharmacy Practice and Pharmaceutics, Faculty of Pharmacy, Hamdard University, Karachi, PakistanDepartment of Pharmaceutics, Faculty of Pharmacy, Hamdard University, Karachi, PakistanDepartment of Pharmacology, Faculty of Pharmacy, Hamdard University, Karachi, PakistanPeritonitis is an infection with a substantial source of morbidity and death. The mortality rate is 10% to 60%. Its etiology may be infection of bacteria, viruses, or fungi. The objective of the current systematic review is to identify the causes of peritonitis and discuss available treatment options. A systematic review was conducted from the literature from January 2012 to December 2022. More than 60 articles were downloaded; after abstracting relevant information from the studies and assessing quality, data was synthesized and presented by PRISMA flow diagram. The most common cause was bacterial infection; followed by fungal and viral infections. Reported organisms were E. coli, Klebsiella spp., Streptococcus spp., M. tuberculosis, C. trachomatis, Pseudomonas spss., C. albicans, C. glabrata, C. krusei, Cryptococcus spp., and Aspergillus spp., and Feline-infectious-corona-virus. Empiric antibiotics therapy covers broad-spectrum antibacterials; antifungal and surgical interventions are treatment options. The acutely ill patient requires combined medical and surgical methods; culture sensitivity is highly advisable to reduce the chances of failure.https://journals.lnh.edu.pk/lnjpc/pdf/7d21a528-b432-4deb-8f8f-74809e5a80af.pdfperitonitisbacteriafungivirusempiric therapy
spellingShingle Sheikh Abdul Khaliq
Muhammad Idrees
Amna Zameer
Peritonitis – Etiology and Treatment Options: A Systematic Review
Liaquat National Journal of Primary Care
peritonitis
bacteria
fungi
virus
empiric therapy
title Peritonitis – Etiology and Treatment Options: A Systematic Review
title_full Peritonitis – Etiology and Treatment Options: A Systematic Review
title_fullStr Peritonitis – Etiology and Treatment Options: A Systematic Review
title_full_unstemmed Peritonitis – Etiology and Treatment Options: A Systematic Review
title_short Peritonitis – Etiology and Treatment Options: A Systematic Review
title_sort peritonitis etiology and treatment options a systematic review
topic peritonitis
bacteria
fungi
virus
empiric therapy
url https://journals.lnh.edu.pk/lnjpc/pdf/7d21a528-b432-4deb-8f8f-74809e5a80af.pdf
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