Dose Regulation Model of Norepinephrine Based on LSTM Network and Clustering Analysis in Sepsis

Sepsis is a life-threatening condition that arises when the body's response to infection causes injury to its own tissues and organs. Despite the advancement of medical diagnosis and treatment technologies, the morbidity and mortality of sepsis are still relatively high. In this paper, a tw...

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Bibliographic Details
Main Authors: Jingming Liu, Minghui Gong, Wei Guo, Chunping Li, Hui Wang, Shuai Zhang, Christopher Nugent
Format: Article
Language:English
Published: Springer 2020-06-01
Series:International Journal of Computational Intelligence Systems
Subjects:
Online Access:https://www.atlantis-press.com/article/125941526/view
Description
Summary:Sepsis is a life-threatening condition that arises when the body's response to infection causes injury to its own tissues and organs. Despite the advancement of medical diagnosis and treatment technologies, the morbidity and mortality of sepsis are still relatively high. In this paper, a two-layer long short-term memory (LSTM) model is proposed to predict the dose of norepinephrine, in order to control the blood pressure of patients. The proposed modeling approach is evaluated using the MIMIC-III dataset, achieving higher performance.
ISSN:1875-6883