Immunoregulatory effects of RGMb in gut inflammation

Immunoregulatory effects of RGMb in gut inflammation

Graft-versus-host disease (GvHD) is a major complication after allogeneic hematopoietic cell transplantation (HCT). Current strategies to prevent GvHD with immunosuppressive drugs carry significant morbidity and may affect the graft-versus-tumor (GVT) effect. Inflammatory bowel disease (IBD) is an i...

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Main Authors: Magdiel Pérez-Cruz, Bettina P. Iliopoulou, Katie Hsu, Hsin-Hsu Wu, Tom Erkers, Kavya Swaminathan, Sai-Wen Tang, Cameron S. Bader, Neeraja Kambham, Bryan Xie, Rosemarie H. Dekruyff, Gordon J. Freeman, Everett Meyer
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
RGMB
GvHD
gut inflammation
colitis
immunoregulation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.960329/full

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