Potential Utility of Synthetic D-Lactate Polymers in Skin Cancer
Increased breakdown of glucose through glycolysis in both aerobic and anaerobic conditions is a hallmark feature of mammalian cancer and leads to increased production of L-lactate. The high-level lactate present within the tumor microenvironment is reused as a crucial biofuel to support rapid cancer...
Main Authors: | Anushka Dikshit, Junqi Lu, Amy E. Ford, Simone Degan, Yingai J. Jin, Huiying Sun, Amanda Nichols, April K.S. Salama, Georgia Beasley, David Gooden, Jennifer Y. Zhang |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-09-01
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Series: | JID Innovations |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2667026721000448 |
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