The Stochastic Approach for SIR Epidemic Models: Do They Help to Increase Information from Raw Data?

The recent outbreak of COVID-19 underlined the need for a fast and trustworthy methodology to identify the features of a pandemic, whose early identification is of help for designing non-pharmaceutical interventions (including lockdown and social distancing) to limit the progression of the disease....

Full description

Bibliographic Details
Main Authors: Alessandro Borri, Pasquale Palumbo, Federico Papa
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Symmetry
Subjects:
Online Access:https://www.mdpi.com/2073-8994/14/11/2330
_version_ 1797466378297409536
author Alessandro Borri
Pasquale Palumbo
Federico Papa
author_facet Alessandro Borri
Pasquale Palumbo
Federico Papa
author_sort Alessandro Borri
collection DOAJ
description The recent outbreak of COVID-19 underlined the need for a fast and trustworthy methodology to identify the features of a pandemic, whose early identification is of help for designing non-pharmaceutical interventions (including lockdown and social distancing) to limit the progression of the disease. A common approach in this context is the parameter identification from deterministic epidemic models, which, unfortunately, cannot take into account the inherent randomness of the epidemic phenomenon, especially in the initial stage; on the other hand, the use of raw data within the framework of a stochastic model is not straightforward. This note investigates the stochastic approach applied to a basic SIR (Susceptible, Infected, Recovered) epidemic model to enhance information from raw data generated in silico. The stochastic model consists of a Continuous-Time Markov Model, describing the epidemic outbreak in terms of stochastic discrete infection and recovery events in a given region, and where independent random paths are associated to different provinces of the same region, which are assumed to share the same set of model parameters. The estimation procedure is based on the building of a loss function that symmetrically weighs first-order and second-order moments, differently from the standard approach that considers a highly asymmetrical choice, exploiting only first-order moments. Instead, we opt for an innovative symmetrical identification approach which exploits both moments. The new approach is specifically proposed to enhance the statistical information content of the raw epidemiological data.
first_indexed 2024-03-09T18:36:05Z
format Article
id doaj.art-52daa5abdb1c484b8ad7715f21a24f55
institution Directory Open Access Journal
issn 2073-8994
language English
last_indexed 2024-03-09T18:36:05Z
publishDate 2022-11-01
publisher MDPI AG
record_format Article
series Symmetry
spelling doaj.art-52daa5abdb1c484b8ad7715f21a24f552023-11-24T07:08:36ZengMDPI AGSymmetry2073-89942022-11-011411233010.3390/sym14112330The Stochastic Approach for SIR Epidemic Models: Do They Help to Increase Information from Raw Data?Alessandro Borri0Pasquale Palumbo1Federico Papa2Institute for Systems Analysis and Computer Science “A. Ruberti” (IASI- CNR), 00185 Rome, ItalyDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza, 20126 Milan, ItalyInstitute for Systems Analysis and Computer Science “A. Ruberti” (IASI- CNR), 00185 Rome, ItalyThe recent outbreak of COVID-19 underlined the need for a fast and trustworthy methodology to identify the features of a pandemic, whose early identification is of help for designing non-pharmaceutical interventions (including lockdown and social distancing) to limit the progression of the disease. A common approach in this context is the parameter identification from deterministic epidemic models, which, unfortunately, cannot take into account the inherent randomness of the epidemic phenomenon, especially in the initial stage; on the other hand, the use of raw data within the framework of a stochastic model is not straightforward. This note investigates the stochastic approach applied to a basic SIR (Susceptible, Infected, Recovered) epidemic model to enhance information from raw data generated in silico. The stochastic model consists of a Continuous-Time Markov Model, describing the epidemic outbreak in terms of stochastic discrete infection and recovery events in a given region, and where independent random paths are associated to different provinces of the same region, which are assumed to share the same set of model parameters. The estimation procedure is based on the building of a loss function that symmetrically weighs first-order and second-order moments, differently from the standard approach that considers a highly asymmetrical choice, exploiting only first-order moments. Instead, we opt for an innovative symmetrical identification approach which exploits both moments. The new approach is specifically proposed to enhance the statistical information content of the raw epidemiological data.https://www.mdpi.com/2073-8994/14/11/2330SIR modelsparameter identificationstochastic approach
spellingShingle Alessandro Borri
Pasquale Palumbo
Federico Papa
The Stochastic Approach for SIR Epidemic Models: Do They Help to Increase Information from Raw Data?
Symmetry
SIR models
parameter identification
stochastic approach
title The Stochastic Approach for SIR Epidemic Models: Do They Help to Increase Information from Raw Data?
title_full The Stochastic Approach for SIR Epidemic Models: Do They Help to Increase Information from Raw Data?
title_fullStr The Stochastic Approach for SIR Epidemic Models: Do They Help to Increase Information from Raw Data?
title_full_unstemmed The Stochastic Approach for SIR Epidemic Models: Do They Help to Increase Information from Raw Data?
title_short The Stochastic Approach for SIR Epidemic Models: Do They Help to Increase Information from Raw Data?
title_sort stochastic approach for sir epidemic models do they help to increase information from raw data
topic SIR models
parameter identification
stochastic approach
url https://www.mdpi.com/2073-8994/14/11/2330
work_keys_str_mv AT alessandroborri thestochasticapproachforsirepidemicmodelsdotheyhelptoincreaseinformationfromrawdata
AT pasqualepalumbo thestochasticapproachforsirepidemicmodelsdotheyhelptoincreaseinformationfromrawdata
AT federicopapa thestochasticapproachforsirepidemicmodelsdotheyhelptoincreaseinformationfromrawdata
AT alessandroborri stochasticapproachforsirepidemicmodelsdotheyhelptoincreaseinformationfromrawdata
AT pasqualepalumbo stochasticapproachforsirepidemicmodelsdotheyhelptoincreaseinformationfromrawdata
AT federicopapa stochasticapproachforsirepidemicmodelsdotheyhelptoincreaseinformationfromrawdata