Post-heparin LPL activity measurement using VLDL as a substrate: a new robust method for routine assessment of plasma triglyceride lipolysis defects.

<h4>Background</h4>Determination of lipoprotein lipase (LPL) activity is important for hyperchylomicronemia diagnosis, but remains both unreliable and cumbersome with current methods. Consequently by using human VLDL as substrate we developed a new LPL assay which does not require sonica...

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Main Authors: Mathilde Di Filippo, Christophe Marçais, Sybil Charrière, Oriane Marmontel, Martine Broyer, Mireille Delay, Micheline Merlin, Axel Nollace, René Valéro, Michel Lagarde, Valérie Pruneta-Deloche, Philippe Moulin, Agnès Sassolas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0096482&type=printable