The Effect of Pulmonary Valve Replacement (PVR) Surgery on Hemodynamics of Patients Who Underwent Repair of Tetralogy of Fallot (TOF)
Introduction: Pulmonary insufficiency (PI) frequently develops in patients who underwent repair of tetralogy of fallot (TOF). The aim of present study was to assess the effect of pulmonary valve replacement (PVR) on hemodynamics of patients who underwent repair of TOF. Methods: This retrospective co...
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| Format: | Article |
| Language: | English |
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Tabriz University of Medical Sciences
2015-09-01
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| Series: | Journal of Cardiovascular and Thoracic Research |
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| Online Access: | http://journals.tbzmed.ac.ir/JCVTR/PDF/JCVTR-7-122.pdf |
| _version_ | 1819131071725305856 |
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| author | Hamid Bigdelian Davoud Mardani Mohsen Sedighi |
| author_facet | Hamid Bigdelian Davoud Mardani Mohsen Sedighi |
| author_sort | Hamid Bigdelian |
| collection | DOAJ |
| description | Introduction: Pulmonary insufficiency (PI) frequently develops in patients who underwent repair of tetralogy of fallot (TOF). The aim of present study was to assess the effect of pulmonary valve replacement (PVR) on hemodynamics of patients who underwent repair of TOF.
Methods: This retrospective cohort carried out between July 2010 and October 2012 among consecutive PVRs of 19 patients who underwent TOF surgery. The PVRs was performed using bioprosthetic (n=17) and mechanical (n=2) valves. Our data was collected during follow up visits within 6 to 12 month after PVR.
Results: Our results show that PVR significantly decreased right ventricular end-diastolic volume (180.89±13.78 vs. 107.21±12.02 ml/m2, P<.01), right ventricular end-systolic volume (105.42±15.98 vs. 58.15±11.67 ml/m2, P<.01), RV mass (47.78±6.20 vs. 30.68±8.95 g/m2, P<.01), and PI (48.21±1.43% vs. 12.68±5.60%, P<.01). Moreover, left ventricular end-diastolic volume significantly increased (78.05±17.21 vs. 90.78±14.82 ml/m2, P<.01) after PVR. The other hemodynamics indexes did not change, significantly.
Conclusion: Despite the controversies about efficacy of PVR after repair of TOF, the remarkable improvement of hemodynamic is a supportive rationale for performing PVR surgery in TOF patients. |
| first_indexed | 2024-12-22T09:09:41Z |
| format | Article |
| id | doaj.art-52df0ddae8fe4a49bd383347aaf8ced4 |
| institution | Directory Open Access Journal |
| issn | 2008-5117 2008-6830 |
| language | English |
| last_indexed | 2024-12-22T09:09:41Z |
| publishDate | 2015-09-01 |
| publisher | Tabriz University of Medical Sciences |
| record_format | Article |
| series | Journal of Cardiovascular and Thoracic Research |
| spelling | doaj.art-52df0ddae8fe4a49bd383347aaf8ced42022-12-21T18:31:29ZengTabriz University of Medical SciencesJournal of Cardiovascular and Thoracic Research2008-51172008-68302015-09-017312212510.15171/jcvtr.2015.26JCVTR_2265_20140922121648The Effect of Pulmonary Valve Replacement (PVR) Surgery on Hemodynamics of Patients Who Underwent Repair of Tetralogy of Fallot (TOF)Hamid Bigdelian0Davoud Mardani1Mohsen Sedighi2Department of Cardiovascular Surgery, Isfahan University of Medical Sciences, Isfahan, IranShahid Chamran Heart Center, Isfahan University of Medical Sciences, Isfahan, IranShahid Chamran Heart Center, Isfahan University of Medical Sciences, Isfahan, IranIntroduction: Pulmonary insufficiency (PI) frequently develops in patients who underwent repair of tetralogy of fallot (TOF). The aim of present study was to assess the effect of pulmonary valve replacement (PVR) on hemodynamics of patients who underwent repair of TOF. Methods: This retrospective cohort carried out between July 2010 and October 2012 among consecutive PVRs of 19 patients who underwent TOF surgery. The PVRs was performed using bioprosthetic (n=17) and mechanical (n=2) valves. Our data was collected during follow up visits within 6 to 12 month after PVR. Results: Our results show that PVR significantly decreased right ventricular end-diastolic volume (180.89±13.78 vs. 107.21±12.02 ml/m2, P<.01), right ventricular end-systolic volume (105.42±15.98 vs. 58.15±11.67 ml/m2, P<.01), RV mass (47.78±6.20 vs. 30.68±8.95 g/m2, P<.01), and PI (48.21±1.43% vs. 12.68±5.60%, P<.01). Moreover, left ventricular end-diastolic volume significantly increased (78.05±17.21 vs. 90.78±14.82 ml/m2, P<.01) after PVR. The other hemodynamics indexes did not change, significantly. Conclusion: Despite the controversies about efficacy of PVR after repair of TOF, the remarkable improvement of hemodynamic is a supportive rationale for performing PVR surgery in TOF patients.http://journals.tbzmed.ac.ir/JCVTR/PDF/JCVTR-7-122.pdfCongenital SurgeryCardiac Magnetic ResonancePulmonary RegurgitationProsthetic Valve |
| spellingShingle | Hamid Bigdelian Davoud Mardani Mohsen Sedighi The Effect of Pulmonary Valve Replacement (PVR) Surgery on Hemodynamics of Patients Who Underwent Repair of Tetralogy of Fallot (TOF) Journal of Cardiovascular and Thoracic Research Congenital Surgery Cardiac Magnetic Resonance Pulmonary Regurgitation Prosthetic Valve |
| title | The Effect of Pulmonary Valve Replacement (PVR) Surgery on Hemodynamics of Patients Who Underwent Repair of Tetralogy of Fallot (TOF) |
| title_full | The Effect of Pulmonary Valve Replacement (PVR) Surgery on Hemodynamics of Patients Who Underwent Repair of Tetralogy of Fallot (TOF) |
| title_fullStr | The Effect of Pulmonary Valve Replacement (PVR) Surgery on Hemodynamics of Patients Who Underwent Repair of Tetralogy of Fallot (TOF) |
| title_full_unstemmed | The Effect of Pulmonary Valve Replacement (PVR) Surgery on Hemodynamics of Patients Who Underwent Repair of Tetralogy of Fallot (TOF) |
| title_short | The Effect of Pulmonary Valve Replacement (PVR) Surgery on Hemodynamics of Patients Who Underwent Repair of Tetralogy of Fallot (TOF) |
| title_sort | effect of pulmonary valve replacement pvr surgery on hemodynamics of patients who underwent repair of tetralogy of fallot tof |
| topic | Congenital Surgery Cardiac Magnetic Resonance Pulmonary Regurgitation Prosthetic Valve |
| url | http://journals.tbzmed.ac.ir/JCVTR/PDF/JCVTR-7-122.pdf |
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