Outpatient monitoring of patients with multisystem inflammatory syndrome (MIS-C): A mini review
IntroductionAs we learn more about the novel multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19 infection, the protocols for long-term follow-up have evolved and only some of these protocols have been published. Here, we review the current literature on follow-up guidelin...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-12-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2022.1069632/full |
| _version_ | 1811177989805703168 |
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| author | Jerin Tresa Jose Elif Seda Selamet Tierney |
| author_facet | Jerin Tresa Jose Elif Seda Selamet Tierney |
| author_sort | Jerin Tresa Jose |
| collection | DOAJ |
| description | IntroductionAs we learn more about the novel multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19 infection, the protocols for long-term follow-up have evolved and only some of these protocols have been published. Here, we review the current literature on follow-up guidelines in MIS-C patients.MethodsWe conducted a PUBMED search of all articles published on “MIS-C” and the term “follow-up” between 2020 and 2022. Inclusion criteria were that (1) the study was an observational study or case series, and (2) the study population included pediatric population who met the diagnostic criteria for MIS-C.ResultsThere were 206 publications on MIS-C and follow-up in the last 2 years with 11 studies that fit the inclusion criteria. These papers were representing 11 different centers and encompassed a total of 343 participants. Seven of the 11 studies had participants follow-up with their cardiologist within 1 month of discharge. Between 12% and 62% of patients within each study had depressed left ventricular ejection fraction (LVEF) at admission. At the initial follow-up visit, five studies showed a normal LVEF in all patients while the other seven studies showed 2%–13% patients continuing to have depressed LVEF. In eight of the 11 studies, 9%–52% of patients had coronary artery dilation at admission. At their initial follow-up visit, 3%–28% of patients continued to have coronary artery dilation.ConclusionThere is some institutional variation in the outpatient follow-up protocols in patients diagnosed with MIS-C. A standardized follow-up guidelines might be helpful to monitor long-term prognosis of these patients. |
| first_indexed | 2024-04-11T06:11:51Z |
| format | Article |
| id | doaj.art-52e0c6369e4e41b987f0b4908073b96e |
| institution | Directory Open Access Journal |
| issn | 2296-2360 |
| language | English |
| last_indexed | 2024-04-11T06:11:51Z |
| publishDate | 2022-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj.art-52e0c6369e4e41b987f0b4908073b96e2022-12-22T04:41:14ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602022-12-011010.3389/fped.2022.10696321069632Outpatient monitoring of patients with multisystem inflammatory syndrome (MIS-C): A mini reviewJerin Tresa JoseElif Seda Selamet TierneyIntroductionAs we learn more about the novel multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19 infection, the protocols for long-term follow-up have evolved and only some of these protocols have been published. Here, we review the current literature on follow-up guidelines in MIS-C patients.MethodsWe conducted a PUBMED search of all articles published on “MIS-C” and the term “follow-up” between 2020 and 2022. Inclusion criteria were that (1) the study was an observational study or case series, and (2) the study population included pediatric population who met the diagnostic criteria for MIS-C.ResultsThere were 206 publications on MIS-C and follow-up in the last 2 years with 11 studies that fit the inclusion criteria. These papers were representing 11 different centers and encompassed a total of 343 participants. Seven of the 11 studies had participants follow-up with their cardiologist within 1 month of discharge. Between 12% and 62% of patients within each study had depressed left ventricular ejection fraction (LVEF) at admission. At the initial follow-up visit, five studies showed a normal LVEF in all patients while the other seven studies showed 2%–13% patients continuing to have depressed LVEF. In eight of the 11 studies, 9%–52% of patients had coronary artery dilation at admission. At their initial follow-up visit, 3%–28% of patients continued to have coronary artery dilation.ConclusionThere is some institutional variation in the outpatient follow-up protocols in patients diagnosed with MIS-C. A standardized follow-up guidelines might be helpful to monitor long-term prognosis of these patients.https://www.frontiersin.org/articles/10.3389/fped.2022.1069632/fullMIS-CCOVID-19follow-upechocardiographyoutpatient MIS-C: multisystem inflammatory syndrome in childrenLVEF: left ventricular ejection fraction |
| spellingShingle | Jerin Tresa Jose Elif Seda Selamet Tierney Outpatient monitoring of patients with multisystem inflammatory syndrome (MIS-C): A mini review Frontiers in Pediatrics MIS-C COVID-19 follow-up echocardiography outpatient MIS-C: multisystem inflammatory syndrome in children LVEF: left ventricular ejection fraction |
| title | Outpatient monitoring of patients with multisystem inflammatory syndrome (MIS-C): A mini review |
| title_full | Outpatient monitoring of patients with multisystem inflammatory syndrome (MIS-C): A mini review |
| title_fullStr | Outpatient monitoring of patients with multisystem inflammatory syndrome (MIS-C): A mini review |
| title_full_unstemmed | Outpatient monitoring of patients with multisystem inflammatory syndrome (MIS-C): A mini review |
| title_short | Outpatient monitoring of patients with multisystem inflammatory syndrome (MIS-C): A mini review |
| title_sort | outpatient monitoring of patients with multisystem inflammatory syndrome mis c a mini review |
| topic | MIS-C COVID-19 follow-up echocardiography outpatient MIS-C: multisystem inflammatory syndrome in children LVEF: left ventricular ejection fraction |
| url | https://www.frontiersin.org/articles/10.3389/fped.2022.1069632/full |
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