Oxidative stress and change of contents of microcells in embryos tissues at experimental trichinellosis
Trichinellosis is accompanied by oxidative stress in cages of embryos of females of rats which is characterized by increase of level of diene conjugates on 63,12 % and malondialdehyde on 71,32 % and as decrease in activity of catalase on 46,62 %, superoxide dismutase on 36,47 %. In tissues of their...
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| Format: | Article |
| Language: | Russian |
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Federal Scientific Centre VIEV
2016-04-01
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| Series: | Российский паразитологический журнал |
| Subjects: | |
| Online Access: | https://vniigis.elpub.ru/jour/article/view/12 |
| _version_ | 1797270549515206656 |
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| author | K. S. Pashinskaya |
| author_facet | K. S. Pashinskaya |
| author_sort | K. S. Pashinskaya |
| collection | DOAJ |
| description | Trichinellosis is accompanied by oxidative stress in cages of embryos of females of rats which is characterized by increase of level of diene conjugates on 63,12 % and malondialdehyde on 71,32 % and as decrease in activity of catalase on 46,62 %, superoxide dismutase on 36,47 %. In tissues of their embryos has shown decrease in the maintenance of vitamins and reduction of concentration of microelements. Therapy of experimental trichinellosis by one anthelmintic (albendazole or mebendazole) does not lead to normalisation of levels of vitamins and minerals in tissues of embryos. Application for complex therapy experimental trichinellosis of pregnant females of rats of a complex of vitamins of antioxidatic character with selenium will neutralize a disbalance of vitamins and minerals in tissues of em-bryos and negative action reactive oxygen species. |
| first_indexed | 2024-03-08T21:41:58Z |
| format | Article |
| id | doaj.art-52e21365ddd44849917ef983426720f7 |
| institution | Directory Open Access Journal |
| issn | 1998-8435 2541-7843 |
| language | Russian |
| last_indexed | 2024-04-25T02:06:02Z |
| publishDate | 2016-04-01 |
| publisher | Federal Scientific Centre VIEV |
| record_format | Article |
| series | Российский паразитологический журнал |
| spelling | doaj.art-52e21365ddd44849917ef983426720f72024-03-07T14:34:26ZrusFederal Scientific Centre VIEVРоссийский паразитологический журнал1998-84352541-78432016-04-0101616712Oxidative stress and change of contents of microcells in embryos tissues at experimental trichinellosisK. S. Pashinskaya0Витебский государственный медицинский университетTrichinellosis is accompanied by oxidative stress in cages of embryos of females of rats which is characterized by increase of level of diene conjugates on 63,12 % and malondialdehyde on 71,32 % and as decrease in activity of catalase on 46,62 %, superoxide dismutase on 36,47 %. In tissues of their embryos has shown decrease in the maintenance of vitamins and reduction of concentration of microelements. Therapy of experimental trichinellosis by one anthelmintic (albendazole or mebendazole) does not lead to normalisation of levels of vitamins and minerals in tissues of embryos. Application for complex therapy experimental trichinellosis of pregnant females of rats of a complex of vitamins of antioxidatic character with selenium will neutralize a disbalance of vitamins and minerals in tissues of em-bryos and negative action reactive oxygen species.https://vniigis.elpub.ru/jour/article/view/12trichinella spiralis, embryos, oxidative stress, vitamins, microcells, complex therapy |
| spellingShingle | K. S. Pashinskaya Oxidative stress and change of contents of microcells in embryos tissues at experimental trichinellosis Российский паразитологический журнал trichinella spiralis, embryos, oxidative stress, vitamins, microcells, complex therapy |
| title | Oxidative stress and change of contents of microcells in embryos tissues at experimental trichinellosis |
| title_full | Oxidative stress and change of contents of microcells in embryos tissues at experimental trichinellosis |
| title_fullStr | Oxidative stress and change of contents of microcells in embryos tissues at experimental trichinellosis |
| title_full_unstemmed | Oxidative stress and change of contents of microcells in embryos tissues at experimental trichinellosis |
| title_short | Oxidative stress and change of contents of microcells in embryos tissues at experimental trichinellosis |
| title_sort | oxidative stress and change of contents of microcells in embryos tissues at experimental trichinellosis |
| topic | trichinella spiralis, embryos, oxidative stress, vitamins, microcells, complex therapy |
| url | https://vniigis.elpub.ru/jour/article/view/12 |
| work_keys_str_mv | AT kspashinskaya oxidativestressandchangeofcontentsofmicrocellsinembryostissuesatexperimentaltrichinellosis |