Prevalent characteristics of human papillomavirus infection in 29,508 women in Jinshan District, Shanghai
Objective: This study aimed to investigate the prevalence characteristics of human papillomavirus (HPV) infections in 29,508 female cases in Jinshan District, Shanghai. Materials and methods: The current research represents a retrospective study that included 29,508 women who received cervical scree...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-11-01
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| Series: | Taiwanese Journal of Obstetrics & Gynecology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1028455922002753 |
| _version_ | 1828119648661405696 |
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| author | Yi Yu Hui-ling Liu Chan-feng He Yan Wang Wen-jie Fu Gui-ping Gan Hui-ling Qu Yan-na Zhou Li Yao |
| author_facet | Yi Yu Hui-ling Liu Chan-feng He Yan Wang Wen-jie Fu Gui-ping Gan Hui-ling Qu Yan-na Zhou Li Yao |
| author_sort | Yi Yu |
| collection | DOAJ |
| description | Objective: This study aimed to investigate the prevalence characteristics of human papillomavirus (HPV) infections in 29,508 female cases in Jinshan District, Shanghai. Materials and methods: The current research represents a retrospective study that included 29,508 women who received cervical screening in the Jinshan Branch of Shanghai Sixth People's Hospital from 2010 to 2020. The overall prevalence, distribution types, age-specific prevalence and annual trends were analysed. Results: The overall HPV infection rate among the patients was 21.97%. They were primarily high-risk HPV (HR-HPV) infections (20.30%) and single HPV infections (15.91%). A general decline in HPV and HR-HPV prevalence was observed with time from 33.52% to 25.45% in 2011 to 21.47% and 20.18% in 2020. The most common HPV genotypes were HPV52, HPV16, HPV58, HPV51, HPV53 and HPV68. The infection rates of HPV genotypes, including HPV6, HPV11, HPV16, HPV18, HPV31, HPV33, HPV35, HPV39, HPV42, HPV43, HPV66 and HPV68, showed overall declines across different years. The age-specific prevalence of total HPV and HR-HPV infections formed an approximate U-shaped curve with two peaks, one in the ≥55 age group (29.75%, 28.43%) and the other in the <25 age group (22.93%, 20.85%). Both total HPV and HR-HPV infection rates decreased to their lowest in the 25–34-year age groups. Conclusions: The prevalence of HPV infections showed a downward tendency with time. Single HPV genotype infections and HR-HPV infections were predominantly detected. The after prevalent characteristics of HPV can help to guide HPV vaccinations and cervical cancer screenings: 1) non-HPV16/HPV18 H R-HPV genotypes were prevalent;2) non-vaccine-covered HPV53, HPV51 and HPV68 were also prevalent; 3) women above the age of 55 years had the highest HPV and HR-HPV infection rates. |
| first_indexed | 2024-04-11T13:51:27Z |
| format | Article |
| id | doaj.art-52e57056c80448389ead826bb111a33c |
| institution | Directory Open Access Journal |
| issn | 1028-4559 |
| language | English |
| last_indexed | 2024-04-11T13:51:27Z |
| publishDate | 2022-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Taiwanese Journal of Obstetrics & Gynecology |
| spelling | doaj.art-52e57056c80448389ead826bb111a33c2022-12-22T04:20:34ZengElsevierTaiwanese Journal of Obstetrics & Gynecology1028-45592022-11-01616971976Prevalent characteristics of human papillomavirus infection in 29,508 women in Jinshan District, ShanghaiYi Yu0Hui-ling Liu1Chan-feng He2Yan Wang3Wen-jie Fu4Gui-ping Gan5Hui-ling Qu6Yan-na Zhou7Li Yao8Department of Obstetrics and Gynecology, Jinshan Branch, Sixth People's Hospital of Shanghai, Shanghai, 201599, China; Corresponding author. Department of Obstetrics and Gynecology, No.147 Jiankang Road, Zhujing Town, Jinshan District, Shanghai.Clinical Laboratory, Jinshan Branch, Sixth People's Hospital of Shanghai, Shanghai, 201599, ChinaDepartment of Obstetrics and Gynecology, Jinshan Branch, Sixth People's Hospital of Shanghai, Shanghai, 201599, ChinaDepartment of Obstetrics and Gynecology, Jinshan Branch, Sixth People's Hospital of Shanghai, Shanghai, 201599, ChinaDepartment of Obstetrics and Gynecology, Jinshan Branch, Sixth People's Hospital of Shanghai, Shanghai, 201599, ChinaDepartment of Obstetrics and Gynecology, Jinshan Branch, Sixth People's Hospital of Shanghai, Shanghai, 201599, ChinaDepartment of Obstetrics and Gynecology, Jinshan Branch, Sixth People's Hospital of Shanghai, Shanghai, 201599, ChinaDepartment of Obstetrics and Gynecology, Jinshan Branch, Sixth People's Hospital of Shanghai, Shanghai, 201599, ChinaClinical Laboratory, Jinshan Branch, Sixth People's Hospital of Shanghai, Shanghai, 201599, ChinaObjective: This study aimed to investigate the prevalence characteristics of human papillomavirus (HPV) infections in 29,508 female cases in Jinshan District, Shanghai. Materials and methods: The current research represents a retrospective study that included 29,508 women who received cervical screening in the Jinshan Branch of Shanghai Sixth People's Hospital from 2010 to 2020. The overall prevalence, distribution types, age-specific prevalence and annual trends were analysed. Results: The overall HPV infection rate among the patients was 21.97%. They were primarily high-risk HPV (HR-HPV) infections (20.30%) and single HPV infections (15.91%). A general decline in HPV and HR-HPV prevalence was observed with time from 33.52% to 25.45% in 2011 to 21.47% and 20.18% in 2020. The most common HPV genotypes were HPV52, HPV16, HPV58, HPV51, HPV53 and HPV68. The infection rates of HPV genotypes, including HPV6, HPV11, HPV16, HPV18, HPV31, HPV33, HPV35, HPV39, HPV42, HPV43, HPV66 and HPV68, showed overall declines across different years. The age-specific prevalence of total HPV and HR-HPV infections formed an approximate U-shaped curve with two peaks, one in the ≥55 age group (29.75%, 28.43%) and the other in the <25 age group (22.93%, 20.85%). Both total HPV and HR-HPV infection rates decreased to their lowest in the 25–34-year age groups. Conclusions: The prevalence of HPV infections showed a downward tendency with time. Single HPV genotype infections and HR-HPV infections were predominantly detected. The after prevalent characteristics of HPV can help to guide HPV vaccinations and cervical cancer screenings: 1) non-HPV16/HPV18 H R-HPV genotypes were prevalent;2) non-vaccine-covered HPV53, HPV51 and HPV68 were also prevalent; 3) women above the age of 55 years had the highest HPV and HR-HPV infection rates.http://www.sciencedirect.com/science/article/pii/S1028455922002753Human papillomavirusHigh-risk HPVPrevalenceGenotypeSingle HPV infection |
| spellingShingle | Yi Yu Hui-ling Liu Chan-feng He Yan Wang Wen-jie Fu Gui-ping Gan Hui-ling Qu Yan-na Zhou Li Yao Prevalent characteristics of human papillomavirus infection in 29,508 women in Jinshan District, Shanghai Taiwanese Journal of Obstetrics & Gynecology Human papillomavirus High-risk HPV Prevalence Genotype Single HPV infection |
| title | Prevalent characteristics of human papillomavirus infection in 29,508 women in Jinshan District, Shanghai |
| title_full | Prevalent characteristics of human papillomavirus infection in 29,508 women in Jinshan District, Shanghai |
| title_fullStr | Prevalent characteristics of human papillomavirus infection in 29,508 women in Jinshan District, Shanghai |
| title_full_unstemmed | Prevalent characteristics of human papillomavirus infection in 29,508 women in Jinshan District, Shanghai |
| title_short | Prevalent characteristics of human papillomavirus infection in 29,508 women in Jinshan District, Shanghai |
| title_sort | prevalent characteristics of human papillomavirus infection in 29 508 women in jinshan district shanghai |
| topic | Human papillomavirus High-risk HPV Prevalence Genotype Single HPV infection |
| url | http://www.sciencedirect.com/science/article/pii/S1028455922002753 |
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