Conformational Rearrangements in the Redox Cycling of NADPH-Cytochrome P450 Reductase from <i>Sorghum bicolor</i> Explored with FRET and Pressure-Perturbation Spectroscopy

Conformational Rearrangements in the Redox Cycling of NADPH-Cytochrome P450 Reductase from <i>Sorghum bicolor</i> Explored with FRET and Pressure-Perturbation Spectroscopy

NADPH-cytochrome P450 reductase (CPR) from <i>Sorghum bicolor</i> (SbCPR) serves as an electron donor for cytochrome P450 essential for monolignol and lignin production in this biofuel crop. The CPR enzymes undergo an ample conformational transition between the closed and open states in...

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Bibliographic Details
Main Authors:	Bixia Zhang, ChulHee Kang, Dmitri R. Davydov
Format:	Article
Language:	English
Published:	MDPI AG 2022-03-01
Series:	Biology
Subjects:	cytochrome P450 reductase conformational change FRET pressure-perturbation spectroscopy protein hydration reduction kinetics
Online Access:	https://www.mdpi.com/2079-7737/11/4/510

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