Intratympanic Administration of Dieckol Prevents Ototoxic Hearing Loss
Objective. Systemic administration of dieckol reportedly ameliorates acute hearing loss. In this study, dieckol was delivered to the inner ear by the intratympanic route. The functional and anatomic effects and safety of dieckol were assessed using the rat ototoxicity model. Materials and methods. D...
Main Authors: | Hui Li, Seung Ha Oh, Hyeon-Cheol Shin, Myung-Whan Suh |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-09-01
|
Series: | Marine Drugs |
Subjects: | |
Online Access: | https://www.mdpi.com/1660-3397/20/10/622 |
Similar Items
-
First Evidence that Ecklonia cava-Derived Dieckol Attenuates MCF-7 Human Breast Carcinoma Cell Migration
by: Eun-Kyung Kim, et al.
Published: (2015-03-01) -
Attenuating Effects of Dieckol on High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease by Decreasing the NLRP3 Inflammasome and Pyroptosis
by: Seyeon Oh, et al.
Published: (2021-05-01) -
Dieckol Reduces Muscle Atrophy by Modulating Angiotensin Type II Type 1 Receptor and NADPH Oxidase in Spontaneously Hypertensive Rats
by: Seyeon Oh, et al.
Published: (2021-09-01) -
Dieckol Decreases Caloric Intake and Attenuates Nonalcoholic Fatty Liver Disease and Hepatic Lymphatic Vessel Dysfunction in High-Fat-Diet-Fed Mice
by: Kyung-A Byun, et al.
Published: (2021-08-01) -
Enhancement of dieckol extraction yield from Ecklonia cava through optimization of major variables in generally recognized as safe solvent-based process
by: Hyeonmi Shin, et al.
Published: (2023-12-01)