Cell-Type-Specific Modulation of Hydrogen Peroxide Cytotoxicity and 4-Hydroxynonenal Binding to Human Cellular Proteins In Vitro by Antioxidant Aloe vera Extract

Cell-Type-Specific Modulation of Hydrogen Peroxide Cytotoxicity and 4-Hydroxynonenal Binding to Human Cellular Proteins In Vitro by Antioxidant Aloe vera Extract

Although Aloe vera contains numerous bioactive components, the activity principles of widely used A. vera extracts are uncertain. Therefore, we analyzed the effects of genuine A. vera aqueous extract (AV) on human cells with respect to the effects of hydrogen peroxide (H2O2) and 4-hydroxynonenal (HN...

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Bibliographic Details
Main Authors: Vera Cesar, Iva Jozić, Lidija Begović, Tea Vuković, Selma Mlinarić, Hrvoje Lepeduš, Suzana Borović Šunjić, Neven Žarković
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Antioxidants
Subjects:
Aloe vera
plant extract
antioxidants
cell growth
oxidative stress
reactive oxygen species (ROS)
hydrogen peroxide
lipid peroxidation
4-hydroxynonenal (HNE)
cell-based ELISA
HNE–protein adducts
microvascular endothelium
Online Access:http://www.mdpi.com/2076-3921/7/10/125

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