Mortality of Patients Infected by COVID-19 with and without Deep-Vein Thrombosis

Background: Current evidence points to a state of hypercoagulability (consequence of hyperinflammation) as an important pathogenic mechanism that contributes to the increase in mortality in cases of COVID-19. The aim of the present study was to investigate the influence of deep-vein thrombosis on mo...

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Main Authors: Jose Maria Pereira de Godoy, Gleison Juliano da Silva Russeff, Carolina Hungaro Costa, Debora Yuri Sato, Desirée Franccini Del Frari Silva, Maria de Fatima Guerreiro Godoy, Henrique Jose Pereira de Godoy, Paulo César Espada
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Medicines
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Online Access:https://www.mdpi.com/2305-6320/8/12/75
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author Jose Maria Pereira de Godoy
Gleison Juliano da Silva Russeff
Carolina Hungaro Costa
Debora Yuri Sato
Desirée Franccini Del Frari Silva
Maria de Fatima Guerreiro Godoy
Henrique Jose Pereira de Godoy
Paulo César Espada
author_facet Jose Maria Pereira de Godoy
Gleison Juliano da Silva Russeff
Carolina Hungaro Costa
Debora Yuri Sato
Desirée Franccini Del Frari Silva
Maria de Fatima Guerreiro Godoy
Henrique Jose Pereira de Godoy
Paulo César Espada
author_sort Jose Maria Pereira de Godoy
collection DOAJ
description Background: Current evidence points to a state of hypercoagulability (consequence of hyperinflammation) as an important pathogenic mechanism that contributes to the increase in mortality in cases of COVID-19. The aim of the present study was to investigate the influence of deep-vein thrombosis on mortality patient’s infected with SARS-CoV-2. Method: A clinical trial was conducted involving 200 consecutive patients with COVID-19—100 patients who were positive for deep-vein thrombosis (venous Doppler ultrasound) and 100 who were negative for deep-vein thrombosis at a public hospital. Results: The mortality rate was 67% in the group positive for DVT and 31% in the group negative for DVT. Conclusion: Deep-vein thrombosis is associated with an increase in mortality in patients with COVID-19 and failures can occur with conventional prophylaxis for deep-vein thrombosis.
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spelling doaj.art-52ea2d269a9942dea90edf6ba411995b2023-11-23T09:29:25ZengMDPI AGMedicines2305-63202021-11-018127510.3390/medicines8120075Mortality of Patients Infected by COVID-19 with and without Deep-Vein ThrombosisJose Maria Pereira de Godoy0Gleison Juliano da Silva Russeff1Carolina Hungaro Costa2Debora Yuri Sato3Desirée Franccini Del Frari Silva4Maria de Fatima Guerreiro Godoy5Henrique Jose Pereira de Godoy6Paulo César Espada7Cardiovascular Surgery Department, Sao Jose do Rio Preto School of Medicine (FAMERP), Undergraduate Medicine Course and <i>Stricto Sensu</i> Postgraduate Course (FAMERP) and CNPq (National Council for Research and Development), São Jose do Rio Preto 15025120, BrazilVascular Surgery Echography Service, Hospital Affiliated with Sao Jose do Rio Preto School of Medicine (FAMERP), São Jose do Rio Preto 15025120, BrazilVascular Surgery Echography Service, Hospital Affiliated with Sao Jose do Rio Preto School of Medicine (FAMERP), São Jose do Rio Preto 15025120, BrazilVascular Surgery Echography Service, Hospital Affiliated with Sao Jose do Rio Preto School of Medicine (FAMERP), São Jose do Rio Preto 15025120, BrazilVascular Surgery Echography Service, Hospital Affiliated with Sao Jose do Rio Preto School of Medicine (FAMERP), São Jose do Rio Preto 15025120, Brazil<i>Stricto Sensu</i> Postgraduate Program, Sao Jose do Rio Preto School of Medicine (FAMERP), Research Group at Godoy Clinic, Sao Jose do Rio Preto 15025120, BrazilDepartment of General Surgery, Sao Jose do Rio Preto School of Medicine (FAMERP), São Jose do Rio Preto 15025120, BrazilTrauma Surgery, Sao Jose do Rio Preto School of Medicine (FAMERP), São Jose do Rio Preto 15025120, BrazilBackground: Current evidence points to a state of hypercoagulability (consequence of hyperinflammation) as an important pathogenic mechanism that contributes to the increase in mortality in cases of COVID-19. The aim of the present study was to investigate the influence of deep-vein thrombosis on mortality patient’s infected with SARS-CoV-2. Method: A clinical trial was conducted involving 200 consecutive patients with COVID-19—100 patients who were positive for deep-vein thrombosis (venous Doppler ultrasound) and 100 who were negative for deep-vein thrombosis at a public hospital. Results: The mortality rate was 67% in the group positive for DVT and 31% in the group negative for DVT. Conclusion: Deep-vein thrombosis is associated with an increase in mortality in patients with COVID-19 and failures can occur with conventional prophylaxis for deep-vein thrombosis.https://www.mdpi.com/2305-6320/8/12/75COVID-19mortalitydeep-vein thrombosisDopplerultrasound
spellingShingle Jose Maria Pereira de Godoy
Gleison Juliano da Silva Russeff
Carolina Hungaro Costa
Debora Yuri Sato
Desirée Franccini Del Frari Silva
Maria de Fatima Guerreiro Godoy
Henrique Jose Pereira de Godoy
Paulo César Espada
Mortality of Patients Infected by COVID-19 with and without Deep-Vein Thrombosis
Medicines
COVID-19
mortality
deep-vein thrombosis
Doppler
ultrasound
title Mortality of Patients Infected by COVID-19 with and without Deep-Vein Thrombosis
title_full Mortality of Patients Infected by COVID-19 with and without Deep-Vein Thrombosis
title_fullStr Mortality of Patients Infected by COVID-19 with and without Deep-Vein Thrombosis
title_full_unstemmed Mortality of Patients Infected by COVID-19 with and without Deep-Vein Thrombosis
title_short Mortality of Patients Infected by COVID-19 with and without Deep-Vein Thrombosis
title_sort mortality of patients infected by covid 19 with and without deep vein thrombosis
topic COVID-19
mortality
deep-vein thrombosis
Doppler
ultrasound
url https://www.mdpi.com/2305-6320/8/12/75
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