Myosin 1f-mediated activation of microglia contributes to the photoreceptor degeneration in a mouse model of retinal detachment

Myosin 1f-mediated activation of microglia contributes to the photoreceptor degeneration in a mouse model of retinal detachment

Abstract Photoreceptor death and neurodegeneration is the leading cause of irreversible vision loss. The inflammatory response of microglia plays an important role in the process of neurodegeneration. In this study, we chose retinal detachment as the model of photoreceptor degeneration. We found Myo...

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Bibliographic Details
Main Authors: Yimin Wang, Xiaohuan Zhao, Min Gao, Xiaoling Wan, Yinong Guo, Yingying Qu, Yuhong Chen, Tong Li, Haiyun Liu, Mei Jiang, Feng Wang, Xiaodong Sun
Format: Article
Language:English
Published: Nature Publishing Group 2021-10-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03983-3

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