Ultrasensitive, label-free, electrochemical detection of miRNA-206 in human plasma: A potential biomarker associated with Alzheimer’s disease

Ultrasensitive, label-free, electrochemical detection of miRNA-206 in human plasma: A potential biomarker associated with Alzheimer’s disease

An impedance-based biosensor for the ultrasensitive, selective, and label-free detection of a blood miRNA associated to Alzheimer disease (AD), miRNA-206, was developed. The principle was grounded in the changes in the charge transfer resistance (RCT) as an effect of intramolecular forces between mi...

Full description

Bibliographic Details
Main Authors:	Amanda Carrico, Loanda R. Cumba, Miguel Medina, Tobias Engel, Robert J. Forster
Format:	Article
Language:	English
Published:	Elsevier 2024-05-01
Series:	Electrochemistry Communications
Subjects:	Label-free Biosensor miRNA-206 Alzheimer disease Electrochemical impedance spectroscopy
Online Access:	http://www.sciencedirect.com/science/article/pii/S138824812400047X

Similar Items

Label-Free Aptasensor for Lysozyme Detection Using Electrochemical Impedance Spectroscopy
by: Dionisia Ortiz-Aguayo, et al.
Published: (2018-01-01)

Aberrant expressions of miRNA-206 target, FN1, in multifactorial Hirschsprung disease
by: Gunadi, et al.
Published: (2019-01-01)

Electrochemical detection of viruses and antibodies: A mini review
by: Miren Ruiz de Eguilaz, et al.
Published: (2020-07-01)

Diagnostic and Prognostic Value of Serum MicroRNA-206 in Patients with Gastric Cancer
by: Cheng-Gong Hou, et al.
Published: (2016-09-01)

A concise overview of advancements in ultrasensitive biosensor development
by: Ammara Shahid, et al.
Published: (2023-11-01)

Glycoprofiling of cancer biomarkers: Label-free electrochemical lectin-based biosensors
by: Pihíková Dominika, et al.
Published: (2015-01-01)

Label-Free Electrochemical Biosensors for the Determination of <i>Flaviviruses</i>: Dengue, Zika, and Japanese Encephalitis
by: Ekaterina Khristunova, et al.
Published: (2020-08-01)

Ultrasensitive Materials for Electrochemical Biosensor Labels
by: Aneesh Koyappayil, et al.
Published: (2020-12-01)

An Overview of Label-free Electrochemical Protein Sensors
by: Eiichi Tamiya, et al.
Published: (2007-12-01)

Electrochemical Impedance Spectroscopy-Based Sensing of Biofilms: A Comprehensive Review
by: Sikander Ameer, et al.
Published: (2023-07-01)

Inflammatory Stimuli Responsive Non-Faradaic, Ultrasensitive Combinatorial Electrochemical Urine Biosensor
by: Antra Ganguly, et al.
Published: (2022-10-01)

Identification of candidate miRNA biomarkers for facioscapulohumeral muscular dystrophy using DUX4-based mouse models
by: Andreia M. Nunes, et al.
Published: (2021-08-01)

miRNA-206-3p alleviates LPS-induced acute lung injury via inhibiting inflammation and pyroptosis through modulating TLR4/NF-κB/NLRP3 pathway
by: Mengchi Chen, et al.
Published: (2024-05-01)

Electrospun Nano- and Microfiber Mesh-Based Transducer for Electrochemical Biosensing Applications
by: Alexander M. Lloyd, et al.
Published: (2023-11-01)

MicroRNA-206 Regulation of Skin Pigmentation in Koi Carp (Cyprinus carpio L.)
by: Zaijie Dong, et al.
Published: (2020-02-01)

Quinone-Based Polymers for Label-Free and Reagentless Electrochemical Immunosensors: Application to Proteins, Antibodies and Pesticides Detection
by: Minh-Chau Pham, et al.
Published: (2013-01-01)

Ultrasensitive Electrochemical Detection of Clostridium perfringens DNA Based Morphology-Dependent DNA Adsorption Properties of CeO2 Nanorods in Dairy Products
by: Xingcan Qian, et al.
Published: (2018-06-01)

An efficiently engineered electrochemical biosensor as a novel and user-friendly electronic device for biosensing of Streptococcus Pneumoniae bacteria
by: Azam Yaghoobi, et al.
Published: (2022-06-01)

Interface Design for CMOS-Integrated Electrochemical Impedance Spectroscopy (EIS) Biosensors
by: Arjang Hassibi, et al.
Published: (2012-10-01)

Functionalization of Graphene Oxide for Label-Free Electrochemical Detection of Hepatic Cancer Cells
by: Samar Damiati, et al.
Published: (2023-05-01)

Electrochemical Impedance Spectroscopy (EIS): Principles, Construction, and Biosensing Applications
by: Hend S. Magar, et al.
Published: (2021-10-01)

Electrochemical Impedance Spectroscopic Sensing of Methamphetamine by a Specific Aptamer
by: Omid Mashinchian, et al.
Published: (2012-05-01)

Kynurenic Acid Electrochemical Immunosensor: Blood-Based Diagnosis of Alzheimer’s Disease
by: Jose Marrugo-Ramírez, et al.
Published: (2021-01-01)

Electrochemical Aptasensor for Detection of Dopamine
by: Hisham Abu-Ali, et al.
Published: (2020-04-01)

Label-Free and Redox Markers-Based Electrochemical Aptasensors for Aflatoxin M1 Detection
by: Stefanos Karapetis, et al.
Published: (2018-12-01)

Impact of Self-Assembled Monolayer Design and Electrochemical Factors on Impedance-Based Biosensing
by: Michael C. Brothers, et al.
Published: (2020-04-01)

Microfluidic Impedance Biosensor Chips Using Sensing Layers Based on DNA-Based Self-Assembled Monolayers for Label-Free Detection of Proteins
by: Khaled Alsabbagh, et al.
Published: (2021-03-01)

CMOS Electrochemical Instrumentation for Biosensor Microsystems: A Review
by: Haitao Li, et al.
Published: (2016-12-01)

Design of Ultrasensitive Electrochemical Aptasensor for Earlier Detection of Hepatitis B Virus
by: Dheyaa Hussein Mohsin, et al.
Published: (2021-06-01)

Impedance Technique-Based Label-Free Electrochemical Aptasensor for Thrombin Using Single-Walled Carbon Nanotubes-Casted Screen-Printed Carbon Electrode
by: Kyungsoon Park
Published: (2022-03-01)

Methodology of Selecting the Optimal Receptor to Create an Electrochemical Immunosensor for Equine Arteritis Virus Protein Detection
by: Mateusz Brodowski, et al.
Published: (2021-09-01)

A label-free electrochemical biosensor for the detection of alpha-thalassemia 1 (SEA deletion) carriers using screen-printed carbon electrodes
by: Areenuch Thamwarokun, et al.
Published: (2023-09-01)

Electrochemical platform for anti-cardiolipin antibody detection in human syphilitic serum
by: Elton M.N. Do Egito, et al.
Published: (2022-01-01)

Model Electrochemical Biosensor for the Detection of Methanol in Aqueous Solutions with Yeast Cells
by: Zala Štukovnik, et al.
Published: (2021-12-01)

Portable Electrochemical Biosensors Based on Microcontrollers for Detection of Viruses: A Review
by: Muhammad Afiq Abdul Ghani, et al.
Published: (2022-08-01)

Label-free electrochemical immunosensor for highly sensitive COVID-19 spike protein detection
by: Qingfeng Zhai, et al.
Published: (2022-11-01)

Mining the Potential of Label-Free Biosensors for In Vitro Antipsychotic Drug Screening
by: Tugba Kilic, et al.
Published: (2018-01-01)

Electrochemical biosensor for simultaneously detection of Tamoxifen
by: Hasret Subak
Published: (2022-12-01)

Aptamer-based label-free electrochemical biosensors for the diagnosis of sickle cell anemia
by: Wjdan A. Arishi, et al.
Published: (2023-09-01)

A Novel PCR-Free Ultrasensitive GQD-Based Label-Free Electrochemical DNA Sensor for Sensitive and Rapid Detection of <i>Francisella tularensis</i>
by: Sumeyra Savas, et al.
Published: (2024-10-01)