Clinical Experience with Genome-Wide Noninvasive Prenatal Screening in a Large Cohort of Twin Pregnancies

Clinical Experience with Genome-Wide Noninvasive Prenatal Screening in a Large Cohort of Twin Pregnancies

Non-invasive prenatal screening (NIPS) in twin gestations has been shown to have high detection rates and low false-positive rates for trisomy 21, as seen in singleton pregnancies, although there have been few large cohort twin studies, genome-wide studies in particular, to date. In this study, we l...

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Bibliographic Details
Main Authors: Luigia De Falco, Giovanni Savarese, Pasquale Savarese, Nadia Petrillo, Monica Ianniello, Raffaella Ruggiero, Teresa Suero, Cosimo Barbato, Alessio Mori, Cristina Ramiro, Luigi Della Corte, Gabriele Saccone, Attilio Di Spiezio Sardo, Antonio Fico
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Genes
Subjects:
non-invasive prenatal testing
genome-wide sequencing
twin pregnancies
failure rate
sensitivity
specificity
Online Access:https://www.mdpi.com/2073-4425/14/5/982

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