Localization of the primary tumor of the colon: аre there essential differences?
Colon cancer is a heterogenous disease with each subtype having a distinct clinical picture and, consequently, different prognosis. Therefore, the tumors can be classified according to their localization: as emerging from the left or right side of the colon. The proximal and distal colon have differ...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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“ABV-press” Publishing house”, LLC
2017-12-01
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| Series: | Тазовая хирургия и онкология |
| Subjects: | |
| Online Access: | https://ok.abvpress.ru/jour/article/view/225 |
| _version_ | 1797705451615289344 |
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| author | M. Yu. Fedyanin A. A. Tryakin S. A. Tjulandin |
| author_facet | M. Yu. Fedyanin A. A. Tryakin S. A. Tjulandin |
| author_sort | M. Yu. Fedyanin |
| collection | DOAJ |
| description | Colon cancer is a heterogenous disease with each subtype having a distinct clinical picture and, consequently, different prognosis. Therefore, the tumors can be classified according to their localization: as emerging from the left or right side of the colon. The proximal and distal colon have different embryogenesis which determines the boundary between the right and left colon at the level of the distal margin of the middle third of the colon. In literature, there’s enough data to consider other differences apart from embryogenesis. Right- and left-side colon tumors differ epidemiologically, clinically and pathomorphologically, molecularly and genetically. This, presumably, explains differences in screening, prevention, and treatment of these tumors. The objective of this review is to analyze differences between colon tumors with different localizations and to determine if such subdivision of colon cancer in clinical practice affects treatment and prevention approaches. |
| first_indexed | 2024-03-12T05:36:23Z |
| format | Article |
| id | doaj.art-52f4836fe0b343449a43a8081c696e4d |
| institution | Directory Open Access Journal |
| issn | 2686-9594 |
| language | Russian |
| last_indexed | 2024-03-12T05:36:23Z |
| publishDate | 2017-12-01 |
| publisher | “ABV-press” Publishing house”, LLC |
| record_format | Article |
| series | Тазовая хирургия и онкология |
| spelling | doaj.art-52f4836fe0b343449a43a8081c696e4d2023-09-03T06:24:41Zrus“ABV-press” Publishing house”, LLCТазовая хирургия и онкология2686-95942017-12-0173354810.17650/2220-3478-2017-7-3-35-48195Localization of the primary tumor of the colon: аre there essential differences?M. Yu. Fedyanin0A. A. Tryakin1S. A. Tjulandin2N.N. Blokhin National Medical Research Center of Oncology of the Ministry of Health of the Russian FederationN.N. Blokhin National Medical Research Center of Oncology of the Ministry of Health of the Russian FederationN.N. Blokhin National Medical Research Center of Oncology of the Ministry of Health of the Russian FederationColon cancer is a heterogenous disease with each subtype having a distinct clinical picture and, consequently, different prognosis. Therefore, the tumors can be classified according to their localization: as emerging from the left or right side of the colon. The proximal and distal colon have different embryogenesis which determines the boundary between the right and left colon at the level of the distal margin of the middle third of the colon. In literature, there’s enough data to consider other differences apart from embryogenesis. Right- and left-side colon tumors differ epidemiologically, clinically and pathomorphologically, molecularly and genetically. This, presumably, explains differences in screening, prevention, and treatment of these tumors. The objective of this review is to analyze differences between colon tumors with different localizations and to determine if such subdivision of colon cancer in clinical practice affects treatment and prevention approaches.https://ok.abvpress.ru/jour/article/view/225colon cancerprimary tumor localizationcolon microfloratargeted therapy |
| spellingShingle | M. Yu. Fedyanin A. A. Tryakin S. A. Tjulandin Localization of the primary tumor of the colon: аre there essential differences? Тазовая хирургия и онкология colon cancer primary tumor localization colon microflora targeted therapy |
| title | Localization of the primary tumor of the colon: аre there essential differences? |
| title_full | Localization of the primary tumor of the colon: аre there essential differences? |
| title_fullStr | Localization of the primary tumor of the colon: аre there essential differences? |
| title_full_unstemmed | Localization of the primary tumor of the colon: аre there essential differences? |
| title_short | Localization of the primary tumor of the colon: аre there essential differences? |
| title_sort | localization of the primary tumor of the colon аre there essential differences |
| topic | colon cancer primary tumor localization colon microflora targeted therapy |
| url | https://ok.abvpress.ru/jour/article/view/225 |
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