Molecular Signalling in Hepatocellular Carcinoma: Role of and Crosstalk among Wnt/β-Catenin, Sonic Hedgehog, Notch and Dickkopf-1

Hepatocellular carcinoma is the sixth most common cancer worldwide. In the majority of cases, there is evidence of existing chronic liver disease from a variety of causes including viral hepatitis B and C, alcoholic liver disease and nonalcoholic steatohepatitis. Identification of the signalling pat...

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Bibliographic Details
Main Authors: Alexandros Giakoustidis, Dimitrios Giakoustidis, Satvinder Mudan, Argyrios Sklavos, Roger Williams
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Canadian Journal of Gastroenterology and Hepatology
Online Access:http://dx.doi.org/10.1155/2015/172356