C57Bl/6N mice have an attenuated lung inflammatory response to dsRNA compared to C57Bl/6J and BALB/c mice

C57Bl/6N mice have an attenuated lung inflammatory response to dsRNA compared to C57Bl/6J and BALB/c mice

Abstract Background Lower respiratory infections caused by ssRNA viruses are a major health burden globally. Translational mouse models are a valuable tool for medical research, including research on respiratory viral infections. In in vivo mouse models, synthetic dsRNA can be used as a surrogate fo...

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Bibliographic Details
Main Authors: Sofia Malm Tillgren, Juan José Nieto-Fontarigo, Samuel Cerps, Sangeetha Ramu, Mandy Menzel, Irma Mahmutovic Persson, Anja Meissner, Hamid Akbarshahi, Lena Uller
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Journal of Inflammation
Subjects:
BALB/c
C57Bl/6J
C57Bl/6N
dsRNA
Poly(I:C)
Inflammation
Online Access:https://doi.org/10.1186/s12950-023-00331-4

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