Changes in functional connectivity following intensive attention training in patients with traumatic brain injury. A pilot study
Objective: To explore functional connectivity after intensive attention training in the chronic phase after traumatic brain injury as clinical evidence indicates that intensive attention training improves attention dysfunction in persons with traumatic brain injury. Design and subjects: A case seri...
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| Format: | Article |
| Language: | English |
| Published: |
Medical Journals Sweden
2024-01-01
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| Series: | Journal of Rehabilitation Medicine - Clinical Communications |
| Subjects: | |
| Online Access: | https://medicaljournalssweden.se/jrm-cc/article/view/12436 |
| _version_ | 1797354083872407552 |
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| author | Gabriela Markovic Tie-Qiang Li Hanna Persson |
| author_facet | Gabriela Markovic Tie-Qiang Li Hanna Persson |
| author_sort | Gabriela Markovic |
| collection | DOAJ |
| description | Objective: To explore functional connectivity after intensive attention training in the chronic phase after traumatic brain injury as clinical evidence indicates that intensive attention training improves attention dysfunction in persons with traumatic brain injury.
Design and subjects: A case series study. Two young adults, 13- and 18-months post traumatic brain injury, with traumatic brain injury induced attention deficits were assigned to 20 h of intensive attention training and neuroimaging.
Methods: Functional magnetic resonance imaging during a psychomotor vigilance test was conducted pre- and post-intervention.
Results: The neuroimaging indicated both increased and decreased connectivity density in frontal, posterior and subcortical brain regions, for some regions with separate change patterns for left and right hemisphere respectively, and an overall reduction in variability in functional connectivity.
Conclusion: The changed and decreased variability of functional connectivity in various brain regions, captured by fMRI during a psychomotor vigilance test after direct attention training in a small sample of persons with traumatic brain injury, suggests further studies of functional connectivity changes in neural networks.
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| first_indexed | 2024-03-08T13:40:10Z |
| format | Article |
| id | doaj.art-52fa7c4131ff421aa7e66e89ef1e42b1 |
| institution | Directory Open Access Journal |
| issn | 2003-0711 |
| language | English |
| last_indexed | 2024-03-08T13:40:10Z |
| publishDate | 2024-01-01 |
| publisher | Medical Journals Sweden |
| record_format | Article |
| series | Journal of Rehabilitation Medicine - Clinical Communications |
| spelling | doaj.art-52fa7c4131ff421aa7e66e89ef1e42b12024-01-16T10:04:07ZengMedical Journals SwedenJournal of Rehabilitation Medicine - Clinical Communications2003-07112024-01-01710.2340/jrmcc.v7.12436Changes in functional connectivity following intensive attention training in patients with traumatic brain injury. A pilot studyGabriela Markovic0Tie-Qiang Li1Hanna Persson2Department of Clinical Sciences, Karolinska Institutet, Danderyd University Hospital, Stockholm, Sweden, Division of Rehabilitation Medicine, Danderyd University Hospital, Stockholm, SwedenDepartment of Clinical Science, Intervention, and Technology, Karolinska Institutet, Stockholm, Sweden; Department of Medical Radiation and Nuclear Medicine, Karolinska University Hospital, Stockholm, SwedenDivision of Rehabilitation Medicine, Danderyd University Hospital, Stockholm, SwedenObjective: To explore functional connectivity after intensive attention training in the chronic phase after traumatic brain injury as clinical evidence indicates that intensive attention training improves attention dysfunction in persons with traumatic brain injury. Design and subjects: A case series study. Two young adults, 13- and 18-months post traumatic brain injury, with traumatic brain injury induced attention deficits were assigned to 20 h of intensive attention training and neuroimaging. Methods: Functional magnetic resonance imaging during a psychomotor vigilance test was conducted pre- and post-intervention. Results: The neuroimaging indicated both increased and decreased connectivity density in frontal, posterior and subcortical brain regions, for some regions with separate change patterns for left and right hemisphere respectively, and an overall reduction in variability in functional connectivity. Conclusion: The changed and decreased variability of functional connectivity in various brain regions, captured by fMRI during a psychomotor vigilance test after direct attention training in a small sample of persons with traumatic brain injury, suggests further studies of functional connectivity changes in neural networks. https://medicaljournalssweden.se/jrm-cc/article/view/12436attention process training (APT)language capacitytraumatic brain injury (TBI)fMRIfunctional connectivity metrics |
| spellingShingle | Gabriela Markovic Tie-Qiang Li Hanna Persson Changes in functional connectivity following intensive attention training in patients with traumatic brain injury. A pilot study Journal of Rehabilitation Medicine - Clinical Communications attention process training (APT) language capacity traumatic brain injury (TBI) fMRI functional connectivity metrics |
| title | Changes in functional connectivity following intensive attention training in patients with traumatic brain injury. A pilot study |
| title_full | Changes in functional connectivity following intensive attention training in patients with traumatic brain injury. A pilot study |
| title_fullStr | Changes in functional connectivity following intensive attention training in patients with traumatic brain injury. A pilot study |
| title_full_unstemmed | Changes in functional connectivity following intensive attention training in patients with traumatic brain injury. A pilot study |
| title_short | Changes in functional connectivity following intensive attention training in patients with traumatic brain injury. A pilot study |
| title_sort | changes in functional connectivity following intensive attention training in patients with traumatic brain injury a pilot study |
| topic | attention process training (APT) language capacity traumatic brain injury (TBI) fMRI functional connectivity metrics |
| url | https://medicaljournalssweden.se/jrm-cc/article/view/12436 |
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