Patients’ views on using human embryonic stem cells to treat Parkinson’s disease: an interview study
Abstract Background Human embryonic stem cells (hESC) as a source for the development of advanced therapy medicinal products are considered for treatment of Parkinson’s disease (PD). Research has shown promising results and opened an avenue of great importance for patients who currently lack a disea...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-10-01
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| Series: | BMC Medical Ethics |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12910-022-00840-6 |
| _version_ | 1797986017726169088 |
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| author | Jennifer Drevin Dag Nyholm Håkan Widner Trinette Van Vliet Jennifer Viberg Johansson Elena Jiltsova Mats Hansson |
| author_facet | Jennifer Drevin Dag Nyholm Håkan Widner Trinette Van Vliet Jennifer Viberg Johansson Elena Jiltsova Mats Hansson |
| author_sort | Jennifer Drevin |
| collection | DOAJ |
| description | Abstract Background Human embryonic stem cells (hESC) as a source for the development of advanced therapy medicinal products are considered for treatment of Parkinson’s disease (PD). Research has shown promising results and opened an avenue of great importance for patients who currently lack a disease modifying therapy. The use of hESC has given rise to moral concerns and been the focus of often heated debates on the moral status of human embryos. Approval for marketing is still pending. Objective To Investigate the perspectives and concerns of patients with PD, patients being the directly concerned stakeholders in the ethical discussion. Methods Qualitative semi-structured interviews related to this new therapy in seventeen patients from two Swedish cities. Results The participants expressed various interests related to the use of human embryos for development of medicinal therapies; however, overall, they were positive towards the use of hESC for treatment of PD. It was deemed important that the donating woman or couple made the choice to donate embryos voluntarily. Furthermore, there were concerns that the industry does not always prioritise the patient over profit; thus, transparency was seen as important. |
| first_indexed | 2024-04-11T07:26:21Z |
| format | Article |
| id | doaj.art-530160f0499542eaa97f5c228d704758 |
| institution | Directory Open Access Journal |
| issn | 1472-6939 |
| language | English |
| last_indexed | 2024-04-11T07:26:21Z |
| publishDate | 2022-10-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Medical Ethics |
| spelling | doaj.art-530160f0499542eaa97f5c228d7047582022-12-22T04:37:03ZengBMCBMC Medical Ethics1472-69392022-10-0123111010.1186/s12910-022-00840-6Patients’ views on using human embryonic stem cells to treat Parkinson’s disease: an interview studyJennifer Drevin0Dag Nyholm1Håkan Widner2Trinette Van Vliet3Jennifer Viberg Johansson4Elena Jiltsova5Mats Hansson6Centre for Research Ethics and Bioethics, Uppsala UniversityDepartment of Medical Sciences, Uppsala University Hospital, Uppsala UniversityNeurology Clinic, Skåne University HospitalNeurology Clinic, Skåne University HospitalCentre for Research Ethics and Bioethics, Uppsala UniversityDepartment of Medical Sciences, Uppsala University Hospital, Uppsala UniversityCentre for Research Ethics and Bioethics, Uppsala UniversityAbstract Background Human embryonic stem cells (hESC) as a source for the development of advanced therapy medicinal products are considered for treatment of Parkinson’s disease (PD). Research has shown promising results and opened an avenue of great importance for patients who currently lack a disease modifying therapy. The use of hESC has given rise to moral concerns and been the focus of often heated debates on the moral status of human embryos. Approval for marketing is still pending. Objective To Investigate the perspectives and concerns of patients with PD, patients being the directly concerned stakeholders in the ethical discussion. Methods Qualitative semi-structured interviews related to this new therapy in seventeen patients from two Swedish cities. Results The participants expressed various interests related to the use of human embryos for development of medicinal therapies; however, overall, they were positive towards the use of hESC for treatment of PD. It was deemed important that the donating woman or couple made the choice to donate embryos voluntarily. Furthermore, there were concerns that the industry does not always prioritise the patient over profit; thus, transparency was seen as important.https://doi.org/10.1186/s12910-022-00840-6hESCATMPHuman embryonic stem cellsAdvanced therapy medicinal productParkinson’s diseaseEthics |
| spellingShingle | Jennifer Drevin Dag Nyholm Håkan Widner Trinette Van Vliet Jennifer Viberg Johansson Elena Jiltsova Mats Hansson Patients’ views on using human embryonic stem cells to treat Parkinson’s disease: an interview study BMC Medical Ethics hESC ATMP Human embryonic stem cells Advanced therapy medicinal product Parkinson’s disease Ethics |
| title | Patients’ views on using human embryonic stem cells to treat Parkinson’s disease: an interview study |
| title_full | Patients’ views on using human embryonic stem cells to treat Parkinson’s disease: an interview study |
| title_fullStr | Patients’ views on using human embryonic stem cells to treat Parkinson’s disease: an interview study |
| title_full_unstemmed | Patients’ views on using human embryonic stem cells to treat Parkinson’s disease: an interview study |
| title_short | Patients’ views on using human embryonic stem cells to treat Parkinson’s disease: an interview study |
| title_sort | patients views on using human embryonic stem cells to treat parkinson s disease an interview study |
| topic | hESC ATMP Human embryonic stem cells Advanced therapy medicinal product Parkinson’s disease Ethics |
| url | https://doi.org/10.1186/s12910-022-00840-6 |
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