PM<sub>2.5</sub> Exacerbates Oxidative Stress and Inflammatory Response through the Nrf2/NF-κB Signaling Pathway in OVA-Induced Allergic Rhinitis Mouse Model

PM<sub>2.5</sub> Exacerbates Oxidative Stress and Inflammatory Response through the Nrf2/NF-κB Signaling Pathway in OVA-Induced Allergic Rhinitis Mouse Model

Air pollution-related particulate matter (PM) exposure reportedly enhances allergic airway inflammation. Some studies have shown an association between PM exposure and a risk for allergic rhinitis (AR). However, the effect of PM for AR is not fully understood. An AR mouse model was developed by intr...

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Bibliographic Details
Main Authors: Chun Hua Piao, Yanjing Fan, Thi Van Nguyen, Hee Soon Shin, Hyoung Tae Kim, Chang Ho Song, Ok Hee Chai
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
particulate matter (PM<sub>2.5</sub>)
allergic rhinitis (AR)
Nrf2
NF-κB
oxidative stress
inflammation
Online Access:https://www.mdpi.com/1422-0067/22/15/8173

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