Structural analysis of resting mouse platelets by 3D-EM reveals an unexpected variation in α-granule shape

Structural analysis of resting mouse platelets by 3D-EM reveals an unexpected variation in α-granule shape

Mice and mouse platelets are major experimental models for hemostasis and thrombosis; however, important physiological data from this model has received little to no quantitative, 3D ultrastructural analysis. We used state-of-the-art, serial block imaging scanning electron microscopy (SBF-SEM, nomin...

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Bibliographic Details
Main Authors: Irina Pokrovskaya, Michael Tobin, Rohan Desai, Maria A. Aronova, Jeffrey A. Kamykowski, Guofeng Zhang, Smita Joshi, Sidney W. Whiteheart, Richard D. Leapman, Brian Storrie
Format: Article
Language:English
Published: Taylor & Francis Group 2021-07-01
Series:Platelets
Subjects:
3d sbf-sem
electron microscopy
mouse
organelles
platelets
α-granules
Online Access:http://dx.doi.org/10.1080/09537104.2020.1799970

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