Septic Shock in Pyogenic Liver Abscess: Clinical Considerations
Background : /Aims: Pyogenic liver abscess (PLA) is a life-threatening condition, despite advances in diagnostic technology and strategies for treatment. A strong predictor of mortality in this condition is septic shock. This study describes clinical, biochemical, and radiologic features in patients...
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| Format: | Article |
| Language: | English |
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Jin Publishing & Printing Co.
2016-05-01
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| Series: | The Korean Journal of Gastroenterology |
| Subjects: | |
| Online Access: | http://www.kjg.or.kr/journal/view.html?doi=10.4166/kjg.2016.67.5.245 |
| _version_ | 1818544853352448000 |
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| author | A Reum Cho Tae Hee Lee Min Ji Park Sun Hee Oh Joo Ah Lee Joo Ho Park Ki Hyun Ryu Hoon Sup Koo Kyung Ho Song Sun Moon Kim Kyu Chan Huh Young Woo Choi Young Woo Kang |
| author_facet | A Reum Cho Tae Hee Lee Min Ji Park Sun Hee Oh Joo Ah Lee Joo Ho Park Ki Hyun Ryu Hoon Sup Koo Kyung Ho Song Sun Moon Kim Kyu Chan Huh Young Woo Choi Young Woo Kang |
| author_sort | A Reum Cho |
| collection | DOAJ |
| description | Background : /Aims: Pyogenic liver abscess (PLA) is a life-threatening condition, despite advances in diagnostic technology and strategies for treatment. A strong predictor of mortality in this condition is septic shock. This study describes clinical, biochemical, and radiologic features in patients with PLA with or without septic shock, with the intent of describing risk factors for septic shock.
Methods : : Of 358 patients with PLA enrolled, 30 suffered septic shock and the remaining 328 did not. We reviewed the medical records including etiologies, underlying diseases, laboratory, radiologic and microbiologic findings, methods of treatment and treatment outcomes.
Results : : The case fatality rate was 6.1%. In univariate analysis, the presence of general weakness, mental change, low platelet level, prolonged PT, high BUN level, high creatinine level, low albumin level, high AST level, high CRP level, abscess size ＞6 cm, the presence of gas-forming abscess, APACHE II score ≥20, and the presence of Klebsiella pneumoniae infection were significantly associated with septic shock. Multivariate analysis showed the presence of mental change (p=0.004), gas-forming abscess (p=0.012), and K. pneumoniae infection (p=0.027) were independent predictors for septic shock.
Conclusion : s: The presence of mental change, gas-forming abscess, and <em>K. pneumoniae</em> infection were independent predictors for septic shock in patients with PLA. (Korean J Gastroenterol 2016;67:245-252) |
| first_indexed | 2024-12-11T22:53:53Z |
| format | Article |
| id | doaj.art-53031b60b9a349b697e91548b8402ddb |
| institution | Directory Open Access Journal |
| issn | 1598-9992 |
| language | English |
| last_indexed | 2024-12-11T22:53:53Z |
| publishDate | 2016-05-01 |
| publisher | Jin Publishing & Printing Co. |
| record_format | Article |
| series | The Korean Journal of Gastroenterology |
| spelling | doaj.art-53031b60b9a349b697e91548b8402ddb2022-12-22T00:47:20ZengJin Publishing & Printing Co.The Korean Journal of Gastroenterology1598-99922016-05-0167524525210.4166/kjg.2016.67.5.245kjg.2016.67.5.245Septic Shock in Pyogenic Liver Abscess: Clinical ConsiderationsA Reum Cho0Tae Hee Lee1Min Ji Park2Sun Hee Oh3Joo Ah Lee4Joo Ho Park5Ki Hyun Ryu6Hoon Sup Koo7Kyung Ho Song8Sun Moon Kim9Kyu Chan Huh10Young Woo Choi11Young Woo Kang12Department of Internal Medicine, Konyang University College of Medicine, Daejeon, KoreaDepartment of Internal Medicine, Konyang University College of Medicine, Daejeon, KoreaDepartment of Internal Medicine, Konyang University College of Medicine, Daejeon, KoreaDepartment of Internal Medicine, Konyang University College of Medicine, Daejeon, KoreaDepartment of Internal Medicine, Konyang University College of Medicine, Daejeon, KoreaDepartment of Internal Medicine, Konyang University College of Medicine, Daejeon, KoreaDepartment of Internal Medicine, Konyang University College of Medicine, Daejeon, KoreaDepartment of Internal Medicine, Konyang University College of Medicine, Daejeon, KoreaDepartment of Internal Medicine, Konyang University College of Medicine, Daejeon, KoreaDepartment of Internal Medicine, Konyang University College of Medicine, Daejeon, KoreaDepartment of Internal Medicine, Konyang University College of Medicine, Daejeon, KoreaDepartment of Internal Medicine, Konyang University College of Medicine, Daejeon, KoreaDepartment of Internal Medicine, Konyang University College of Medicine, Daejeon, KoreaBackground : /Aims: Pyogenic liver abscess (PLA) is a life-threatening condition, despite advances in diagnostic technology and strategies for treatment. A strong predictor of mortality in this condition is septic shock. This study describes clinical, biochemical, and radiologic features in patients with PLA with or without septic shock, with the intent of describing risk factors for septic shock. Methods : : Of 358 patients with PLA enrolled, 30 suffered septic shock and the remaining 328 did not. We reviewed the medical records including etiologies, underlying diseases, laboratory, radiologic and microbiologic findings, methods of treatment and treatment outcomes. Results : : The case fatality rate was 6.1%. In univariate analysis, the presence of general weakness, mental change, low platelet level, prolonged PT, high BUN level, high creatinine level, low albumin level, high AST level, high CRP level, abscess size ＞6 cm, the presence of gas-forming abscess, APACHE II score ≥20, and the presence of Klebsiella pneumoniae infection were significantly associated with septic shock. Multivariate analysis showed the presence of mental change (p=0.004), gas-forming abscess (p=0.012), and K. pneumoniae infection (p=0.027) were independent predictors for septic shock. Conclusion : s: The presence of mental change, gas-forming abscess, and <em>K. pneumoniae</em> infection were independent predictors for septic shock in patients with PLA. (Korean J Gastroenterol 2016;67:245-252)http://www.kjg.or.kr/journal/view.html?doi=10.4166/kjg.2016.67.5.245Pyogenic liver abscessSeptic shockMortalityAPACHE IIKlebsiella pneumoniae |
| spellingShingle | A Reum Cho Tae Hee Lee Min Ji Park Sun Hee Oh Joo Ah Lee Joo Ho Park Ki Hyun Ryu Hoon Sup Koo Kyung Ho Song Sun Moon Kim Kyu Chan Huh Young Woo Choi Young Woo Kang Septic Shock in Pyogenic Liver Abscess: Clinical Considerations The Korean Journal of Gastroenterology Pyogenic liver abscess Septic shock Mortality APACHE II Klebsiella pneumoniae |
| title | Septic Shock in Pyogenic Liver Abscess: Clinical Considerations |
| title_full | Septic Shock in Pyogenic Liver Abscess: Clinical Considerations |
| title_fullStr | Septic Shock in Pyogenic Liver Abscess: Clinical Considerations |
| title_full_unstemmed | Septic Shock in Pyogenic Liver Abscess: Clinical Considerations |
| title_short | Septic Shock in Pyogenic Liver Abscess: Clinical Considerations |
| title_sort | septic shock in pyogenic liver abscess clinical considerations |
| topic | Pyogenic liver abscess Septic shock Mortality APACHE II Klebsiella pneumoniae |
| url | http://www.kjg.or.kr/journal/view.html?doi=10.4166/kjg.2016.67.5.245 |
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