Short-term prophylaxis with ciprofloxacin in extended 16-core prostate biopsy

Objective To evaluate the safety, efficacy and possible complications of 16-core transrectal prostate biopsies using two doses of ciprofloxacin for prophylaxis of infectious complications. Materials and Methods Sixteen-core prostate biopsies were performed on a number of patients with different sign...

Full description

Bibliographic Details
Main Authors: Renato Caretta Chambó, Fábio Hissachi Tsuji, Hamilton Akihissa Yamamoto, Carlos Márcio Nóbrega de Jesus
Format: Article
Language:English
Published: Sociedade Brasileira de Urologia 2015-02-01
Series:International Brazilian Journal of Urology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382015000100046&lng=en&tlng=en
_version_ 1811283984061038592
author Renato Caretta Chambó
Fábio Hissachi Tsuji
Hamilton Akihissa Yamamoto
Carlos Márcio Nóbrega de Jesus
author_facet Renato Caretta Chambó
Fábio Hissachi Tsuji
Hamilton Akihissa Yamamoto
Carlos Márcio Nóbrega de Jesus
author_sort Renato Caretta Chambó
collection DOAJ
description Objective To evaluate the safety, efficacy and possible complications of 16-core transrectal prostate biopsies using two doses of ciprofloxacin for prophylaxis of infectious complications. Materials and Methods Sixteen-core prostate biopsies were performed on a number of patients with different signs of potential prostate cancer. Complications were assessed both during the procedure and one week later. After the procedure, urine samples were collected for culture. The rate of post-biopsy complications, hospital visits and hospitalizations were also analyzed. Ciprofloxacin (500 mg) was administered two hours before, and eight hours after the procedure. Results The overall rate of post-biopsy complications was 87.32%, being 5.4% of those considered major complications due to hemorrhage, or to urinary retention. Eight patients required hospital treatment post-biopsy. Fever occurred in just one patient (0.29%). There was no incidence of orchitis, epididymitis, prostatitis, septicemia, hospitalization, or death. The urine culture showed positive results in five patients (2.15%). Conclusion One-day prophylaxis with ciprofloxacin proved to be safe and effective in the prevention of infectious complications following 16-core prostate biopsies.
first_indexed 2024-04-13T02:21:49Z
format Article
id doaj.art-530494f045fc4738b0df5b8aea87ae72
institution Directory Open Access Journal
issn 1677-6119
language English
last_indexed 2024-04-13T02:21:49Z
publishDate 2015-02-01
publisher Sociedade Brasileira de Urologia
record_format Article
series International Brazilian Journal of Urology
spelling doaj.art-530494f045fc4738b0df5b8aea87ae722022-12-22T03:06:55ZengSociedade Brasileira de UrologiaInternational Brazilian Journal of Urology1677-61192015-02-01411465610.1590/S1677-5538.IBJU.2015.01.08S1677-55382015000100046Short-term prophylaxis with ciprofloxacin in extended 16-core prostate biopsyRenato Caretta ChambóFábio Hissachi TsujiHamilton Akihissa YamamotoCarlos Márcio Nóbrega de JesusObjective To evaluate the safety, efficacy and possible complications of 16-core transrectal prostate biopsies using two doses of ciprofloxacin for prophylaxis of infectious complications. Materials and Methods Sixteen-core prostate biopsies were performed on a number of patients with different signs of potential prostate cancer. Complications were assessed both during the procedure and one week later. After the procedure, urine samples were collected for culture. The rate of post-biopsy complications, hospital visits and hospitalizations were also analyzed. Ciprofloxacin (500 mg) was administered two hours before, and eight hours after the procedure. Results The overall rate of post-biopsy complications was 87.32%, being 5.4% of those considered major complications due to hemorrhage, or to urinary retention. Eight patients required hospital treatment post-biopsy. Fever occurred in just one patient (0.29%). There was no incidence of orchitis, epididymitis, prostatitis, septicemia, hospitalization, or death. The urine culture showed positive results in five patients (2.15%). Conclusion One-day prophylaxis with ciprofloxacin proved to be safe and effective in the prevention of infectious complications following 16-core prostate biopsies.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382015000100046&lng=en&tlng=enprostateprostatic neoplasmsbiopsycomplications
spellingShingle Renato Caretta Chambó
Fábio Hissachi Tsuji
Hamilton Akihissa Yamamoto
Carlos Márcio Nóbrega de Jesus
Short-term prophylaxis with ciprofloxacin in extended 16-core prostate biopsy
International Brazilian Journal of Urology
prostate
prostatic neoplasms
biopsy
complications
title Short-term prophylaxis with ciprofloxacin in extended 16-core prostate biopsy
title_full Short-term prophylaxis with ciprofloxacin in extended 16-core prostate biopsy
title_fullStr Short-term prophylaxis with ciprofloxacin in extended 16-core prostate biopsy
title_full_unstemmed Short-term prophylaxis with ciprofloxacin in extended 16-core prostate biopsy
title_short Short-term prophylaxis with ciprofloxacin in extended 16-core prostate biopsy
title_sort short term prophylaxis with ciprofloxacin in extended 16 core prostate biopsy
topic prostate
prostatic neoplasms
biopsy
complications
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382015000100046&lng=en&tlng=en
work_keys_str_mv AT renatocarettachambo shorttermprophylaxiswithciprofloxacininextended16coreprostatebiopsy
AT fabiohissachitsuji shorttermprophylaxiswithciprofloxacininextended16coreprostatebiopsy
AT hamiltonakihissayamamoto shorttermprophylaxiswithciprofloxacininextended16coreprostatebiopsy
AT carlosmarcionobregadejesus shorttermprophylaxiswithciprofloxacininextended16coreprostatebiopsy