Peppermint essential oil: its phytochemistry, biological activity, pharmacological effect and application
Mentha (also known as peppermint), a genus of plants in the taxonomic family Lamiaceae (mint family), is widely distributed throughout temperate regions of the world. Mentha contains various constituents that are classified as peppermint essential oil (PEO) and non-essential components. PEO, consist...
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Format: | Article |
Language: | English |
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Elsevier
2022-10-01
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Series: | Biomedicine & Pharmacotherapy |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S0753332222009489 |
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author | Hui Zhao Shan Ren Han Yang Shun Tang Chenyang Guo Maolun Liu Qiu Tao Tianqi Ming Haibo Xu |
author_facet | Hui Zhao Shan Ren Han Yang Shun Tang Chenyang Guo Maolun Liu Qiu Tao Tianqi Ming Haibo Xu |
author_sort | Hui Zhao |
collection | DOAJ |
description | Mentha (also known as peppermint), a genus of plants in the taxonomic family Lamiaceae (mint family), is widely distributed throughout temperate regions of the world. Mentha contains various constituents that are classified as peppermint essential oil (PEO) and non-essential components. PEO, consisting mainly of menthol, menthone, neomenthol and iso-menthone, is a mixture of volatile metabolites with anti-inflammatory, antibacterial, antiviral, scolicidal, immunomodulatory, antitumor, neuroprotective, antifatigue and antioxidant activities. Mounting evidence indicates that PEO may pharmacologically protect gastrointestinal, liver, kidney, skin, respiratory, brain and nervous systems, and exert hypoglycemic and hypolipidemic effects. Clinically, PEO is used for gastrointestinal and dermatological diseases, postoperative adjuvant therapy and other fields. This review aims to address the advances in the extraction and isolation of PEO, its biological activities, pharmacological effects, toxicity and applications, with an emphasis on the efficacy of PEO on burn wounds and psoriasis, providing a comprehensive foundation for research, development and application of PEO in future. |
first_indexed | 2024-04-12T23:06:55Z |
format | Article |
id | doaj.art-5307a014e0eb4b4eb806fad48d75ca6d |
institution | Directory Open Access Journal |
issn | 0753-3322 |
language | English |
last_indexed | 2024-04-12T23:06:55Z |
publishDate | 2022-10-01 |
publisher | Elsevier |
record_format | Article |
series | Biomedicine & Pharmacotherapy |
spelling | doaj.art-5307a014e0eb4b4eb806fad48d75ca6d2022-12-22T03:12:53ZengElsevierBiomedicine & Pharmacotherapy0753-33222022-10-01154113559Peppermint essential oil: its phytochemistry, biological activity, pharmacological effect and applicationHui Zhao0Shan Ren1Han Yang2Shun Tang3Chenyang Guo4Maolun Liu5Qiu Tao6Tianqi Ming7Haibo Xu8State Key Laboratory of Southwestern Chinese Medicine Resources, Department of Pharmacology, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China; Department of Pharmacology, School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450000, ChinaState Key Laboratory of Southwestern Chinese Medicine Resources, Department of Pharmacology, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, ChinaState Key Laboratory of Southwestern Chinese Medicine Resources, Department of Pharmacology, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, ChinaState Key Laboratory of Southwestern Chinese Medicine Resources, Department of Pharmacology, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, ChinaDepartment of Pharmacology, School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450000, ChinaState Key Laboratory of Southwestern Chinese Medicine Resources, Department of Pharmacology, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, ChinaState Key Laboratory of Southwestern Chinese Medicine Resources, Department of Pharmacology, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, ChinaState Key Laboratory of Southwestern Chinese Medicine Resources, Department of Pharmacology, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, ChinaState Key Laboratory of Southwestern Chinese Medicine Resources, Department of Pharmacology, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China; Correspondence to: State Key Laboratory of Southwestern Chinese Medicine Resources, Department of Pharmacology, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.Mentha (also known as peppermint), a genus of plants in the taxonomic family Lamiaceae (mint family), is widely distributed throughout temperate regions of the world. Mentha contains various constituents that are classified as peppermint essential oil (PEO) and non-essential components. PEO, consisting mainly of menthol, menthone, neomenthol and iso-menthone, is a mixture of volatile metabolites with anti-inflammatory, antibacterial, antiviral, scolicidal, immunomodulatory, antitumor, neuroprotective, antifatigue and antioxidant activities. Mounting evidence indicates that PEO may pharmacologically protect gastrointestinal, liver, kidney, skin, respiratory, brain and nervous systems, and exert hypoglycemic and hypolipidemic effects. Clinically, PEO is used for gastrointestinal and dermatological diseases, postoperative adjuvant therapy and other fields. This review aims to address the advances in the extraction and isolation of PEO, its biological activities, pharmacological effects, toxicity and applications, with an emphasis on the efficacy of PEO on burn wounds and psoriasis, providing a comprehensive foundation for research, development and application of PEO in future.http://www.sciencedirect.com/science/article/pii/S0753332222009489peppermint essential oilMenthaPhytochemistryBiological activityPharmacological effectApplication |
spellingShingle | Hui Zhao Shan Ren Han Yang Shun Tang Chenyang Guo Maolun Liu Qiu Tao Tianqi Ming Haibo Xu Peppermint essential oil: its phytochemistry, biological activity, pharmacological effect and application Biomedicine & Pharmacotherapy peppermint essential oil Mentha Phytochemistry Biological activity Pharmacological effect Application |
title | Peppermint essential oil: its phytochemistry, biological activity, pharmacological effect and application |
title_full | Peppermint essential oil: its phytochemistry, biological activity, pharmacological effect and application |
title_fullStr | Peppermint essential oil: its phytochemistry, biological activity, pharmacological effect and application |
title_full_unstemmed | Peppermint essential oil: its phytochemistry, biological activity, pharmacological effect and application |
title_short | Peppermint essential oil: its phytochemistry, biological activity, pharmacological effect and application |
title_sort | peppermint essential oil its phytochemistry biological activity pharmacological effect and application |
topic | peppermint essential oil Mentha Phytochemistry Biological activity Pharmacological effect Application |
url | http://www.sciencedirect.com/science/article/pii/S0753332222009489 |
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