Peppermint essential oil: its phytochemistry, biological activity, pharmacological effect and application

Mentha (also known as peppermint), a genus of plants in the taxonomic family Lamiaceae (mint family), is widely distributed throughout temperate regions of the world. Mentha contains various constituents that are classified as peppermint essential oil (PEO) and non-essential components. PEO, consist...

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Main Authors: Hui Zhao, Shan Ren, Han Yang, Shun Tang, Chenyang Guo, Maolun Liu, Qiu Tao, Tianqi Ming, Haibo Xu
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222009489
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author Hui Zhao
Shan Ren
Han Yang
Shun Tang
Chenyang Guo
Maolun Liu
Qiu Tao
Tianqi Ming
Haibo Xu
author_facet Hui Zhao
Shan Ren
Han Yang
Shun Tang
Chenyang Guo
Maolun Liu
Qiu Tao
Tianqi Ming
Haibo Xu
author_sort Hui Zhao
collection DOAJ
description Mentha (also known as peppermint), a genus of plants in the taxonomic family Lamiaceae (mint family), is widely distributed throughout temperate regions of the world. Mentha contains various constituents that are classified as peppermint essential oil (PEO) and non-essential components. PEO, consisting mainly of menthol, menthone, neomenthol and iso-menthone, is a mixture of volatile metabolites with anti-inflammatory, antibacterial, antiviral, scolicidal, immunomodulatory, antitumor, neuroprotective, antifatigue and antioxidant activities. Mounting evidence indicates that PEO may pharmacologically protect gastrointestinal, liver, kidney, skin, respiratory, brain and nervous systems, and exert hypoglycemic and hypolipidemic effects. Clinically, PEO is used for gastrointestinal and dermatological diseases, postoperative adjuvant therapy and other fields. This review aims to address the advances in the extraction and isolation of PEO, its biological activities, pharmacological effects, toxicity and applications, with an emphasis on the efficacy of PEO on burn wounds and psoriasis, providing a comprehensive foundation for research, development and application of PEO in future.
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spelling doaj.art-5307a014e0eb4b4eb806fad48d75ca6d2022-12-22T03:12:53ZengElsevierBiomedicine & Pharmacotherapy0753-33222022-10-01154113559Peppermint essential oil: its phytochemistry, biological activity, pharmacological effect and applicationHui Zhao0Shan Ren1Han Yang2Shun Tang3Chenyang Guo4Maolun Liu5Qiu Tao6Tianqi Ming7Haibo Xu8State Key Laboratory of Southwestern Chinese Medicine Resources, Department of Pharmacology, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China; Department of Pharmacology, School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450000, ChinaState Key Laboratory of Southwestern Chinese Medicine Resources, Department of Pharmacology, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, ChinaState Key Laboratory of Southwestern Chinese Medicine Resources, Department of Pharmacology, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, ChinaState Key Laboratory of Southwestern Chinese Medicine Resources, Department of Pharmacology, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, ChinaDepartment of Pharmacology, School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450000, ChinaState Key Laboratory of Southwestern Chinese Medicine Resources, Department of Pharmacology, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, ChinaState Key Laboratory of Southwestern Chinese Medicine Resources, Department of Pharmacology, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, ChinaState Key Laboratory of Southwestern Chinese Medicine Resources, Department of Pharmacology, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, ChinaState Key Laboratory of Southwestern Chinese Medicine Resources, Department of Pharmacology, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China; Correspondence to: State Key Laboratory of Southwestern Chinese Medicine Resources, Department of Pharmacology, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.Mentha (also known as peppermint), a genus of plants in the taxonomic family Lamiaceae (mint family), is widely distributed throughout temperate regions of the world. Mentha contains various constituents that are classified as peppermint essential oil (PEO) and non-essential components. PEO, consisting mainly of menthol, menthone, neomenthol and iso-menthone, is a mixture of volatile metabolites with anti-inflammatory, antibacterial, antiviral, scolicidal, immunomodulatory, antitumor, neuroprotective, antifatigue and antioxidant activities. Mounting evidence indicates that PEO may pharmacologically protect gastrointestinal, liver, kidney, skin, respiratory, brain and nervous systems, and exert hypoglycemic and hypolipidemic effects. Clinically, PEO is used for gastrointestinal and dermatological diseases, postoperative adjuvant therapy and other fields. This review aims to address the advances in the extraction and isolation of PEO, its biological activities, pharmacological effects, toxicity and applications, with an emphasis on the efficacy of PEO on burn wounds and psoriasis, providing a comprehensive foundation for research, development and application of PEO in future.http://www.sciencedirect.com/science/article/pii/S0753332222009489peppermint essential oilMenthaPhytochemistryBiological activityPharmacological effectApplication
spellingShingle Hui Zhao
Shan Ren
Han Yang
Shun Tang
Chenyang Guo
Maolun Liu
Qiu Tao
Tianqi Ming
Haibo Xu
Peppermint essential oil: its phytochemistry, biological activity, pharmacological effect and application
Biomedicine & Pharmacotherapy
peppermint essential oil
Mentha
Phytochemistry
Biological activity
Pharmacological effect
Application
title Peppermint essential oil: its phytochemistry, biological activity, pharmacological effect and application
title_full Peppermint essential oil: its phytochemistry, biological activity, pharmacological effect and application
title_fullStr Peppermint essential oil: its phytochemistry, biological activity, pharmacological effect and application
title_full_unstemmed Peppermint essential oil: its phytochemistry, biological activity, pharmacological effect and application
title_short Peppermint essential oil: its phytochemistry, biological activity, pharmacological effect and application
title_sort peppermint essential oil its phytochemistry biological activity pharmacological effect and application
topic peppermint essential oil
Mentha
Phytochemistry
Biological activity
Pharmacological effect
Application
url http://www.sciencedirect.com/science/article/pii/S0753332222009489
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